Spot diagnoses

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An exam favourite spot diagnosis (granular cell tumour).

Spot diagnoses are (microscopic) diagnoses one can make on the spot. They are ideal for bell-ringer type exams.

There is a separate article for gross spot diagnoses.

If you are looking for questions for review/practice, take a look at the quizzes page for quick ones, and cases page for longer ones.

Diagnosis Site Notes
Pingueculum Eye
Pterygium Eye
Ameloblastoma Head and neck pathology
Inverted papilloma Head and neck pathology
Papilloma Head and neck pathology
Nasopharyngeal angiofibroma Head and neck pathology
Sinonasal papilloma Head and neck pathology
Branchial cleft cyst Head and neck pathology
Granular cell tumour Head and neck pathology
Keloid Head and neck pathology
Paraganglioma Head and neck pathology
Amyloid Head and neck pathology
Mucormycosis Head and neck pathology
Fibrous dysplasia Head and neck pathology
Rhabdomyoma Head and neck pathology
Acinic cell carcinoma Salivary gland
Adenoid cystic carcinoma Salivary gland
Benign lymphoepithelial lesion Salivary gland
Carcinoma ex pleomorphic adenoma Salivary gland
Mucoepidermoid carcinoma Salivary gland
Pleomorphic adenoma Salivary gland
Warthin tumour Salivary gland
De-Quervain's thyroiditis Thyroid gland
Follicular adenoma Thyroid gland
Follicular carcinoma Thyroid gland
Granulomatous thyroiditis Thyroid gland
Hashimoto thyroiditis Thyroid gland
Hurthle cell adenoma Thyroid gland
Medullary thyroid carcinoma Thyroid gland
Nodular hyperplasia Thyroid gland
Papillary thyroid carcinoma Thyroid gland
Papillary thyroid carcinoma follicular variant Thyroid gland
Papillary thyroid carcinoma tall cell variant Thyroid gland
Papillary thyroid carcinoma columnar cell variant Thyroid gland
Papillary thyroid carcinoma cribriform-morular variant Thyroid gland
Parathyroid adenoma Parathyroid gland
Thymoma Thymus
Adrenal adenoma Adrenal gland
Adrenal cortical carcinoma Adrenal gland
Adrenal gland with cytomegaly Adrenal gland
Pheochromocytoma Adrenal gland
Myelolipoma Adrenal gland
Adenoid cystic carcinoma Pulmonary pathology
Thymic carcinoma Pulmonary pathology
Small cell carcinoma Pulmonary pathology
Nodular sclerosis Hodgkin lymphoma Pulmonary pathology
Plasma cell granuloma Pulmonary pathology Inflammatory myofibroblastic tumour
Eosinophilic granuloma of the lung Pulmonary pathology
Silicone granuloma Pulmonary pathology
Sarcoidosis Pulmonary pathology
Wegener granulomatosis Pulmonary pathology
Ferruginous body Pulmonary pathology
Adenocarcinoma of the lung Pulmonary pathology
Diffuse alveolar damage Pulmonary pathology Histology of ARDS
Aspergillosis Pulmonary pathology
Pneumocystis pneumonia Pulmonary pathology
Aspiration pneumonia Pulmonary pathology
Atypical lung carcinoid tumour Pulmonary pathology
Organizing pneumonia Pulmonary pathology
Bronchioloalveolar carcinoma Pulmonary pathology
Small cell carcinoma Pulmonary pathology
Carcinoid lung tumour Pulmonary pathology
Carcinoid tumourlet Pulmonary pathology Lung tumourlet
Centrilobular emphysema Pulmonary pathology
CMV pneumonia Pulmonary pathology
Coal worker lung Pulmonary pathology
CPAM Pulmonary pathology
Pulmonary hamartoma Pulmonary pathology
Hyaline membrane disease Pulmonary pathology Respiratory distress syndrome
Lobar pneumonia Pulmonary pathology
Mesothelioma Pulmonary pathology
Solitary fibrous tumour Pulmonary pathology
Acute pyelonephritis Medical renal disease
Chronic pyelonephritis Medical renal disease
Xanthogranulomatous pyelonephritis Medical renal disease
Crescentic glomerulonephritis Medical renal disease
Diabetic nephropathy Medical renal disease
Hypertensive kidney Medical renal disease
Membranous glomerulonephritis Medical renal disease
Myeloma of kidney Renal tumours
Angiomyolipoma Renal tumours
Chromophobe renal cell carcinoma Renal tumours
Mesonephric adenoma Renal tumours
Renal oncocytoma Renal tumours
Papillary renal cell carcinoma Renal tumours
Sarcomatoid renal cell carcinoma Renal tumours
Urothelial carcinoma Renal tumours
Clear cell renal cell carcinoma Renal tumours
Basal cell hyperplasia of the prostate Prostate gland
Benign prostatic hyperplasia (BPH) Prostate gland
Urethral caruncle Urothelium
Cystitis cystica et glandularis Urothelium
Granulomatous orchitis Testis
Granulomatous prostatitis Prostate gland
Prostatic infarction Prostate gland
Inverted papilloma of the bladder Urinary bladder
Malakoplakia Urinary bladder
Mixed germ cell tumour Testis
Prostatic adenocarcinoma Prostate gland
Rhabdomyosarcoma of the urinary bladder Urinary bladder
Urinary bladder squamous cell carcinoma Urinary bladder
Schistosomiasis Urinary bladder
Seminoma Testis
Testicular atrophy Testis
Sperm granuloma Testis
Spermatocytic tumour Testis
Teratoma of testis Testis
Urothelial carcinoma in situ Urothelium
Vasitis nodosa Vas deferens
Adenomatoid tumour Genitourinary pathology
Lipoma of the spermatic cord Genitourinary pathology Lipoma
Balanitis xerotica obliterans Genitourinary pathology Lichen sclerosus
Basal cell carcinoma (BCC) Dermatopathology
Acute eczematous dermatitis Dermatopathology
Basal cell carcinoma sclerosing variant Dermatopathology
Trichofolliculoma Dermatopathology
Blue nevus Dermatopathology
Bowen disease Dermatopathology SCC in situ
Verruca vulgaris Dermatopathology Verruca plana similar
Chondroid syringoma Dermatopathology
Compound nevus Dermatopathology
Congenital nevus Dermatopathology
Dysplastic nevus Dermatopathology
Spitz nevus Dermatopathology
Dermal cylindroma Dermatopathology
Nodular hidradenoma Dermatopathology
Dermatitis herpetiformis Dermatopathology
Dermatofibroma Dermatopathology
Epidermal inclusion cyst Dermatopathology
Extramammary Paget disease Dermatopathology
Metastatic signet ring cell carcinoma Dermatopathology
Glomus tumour Dermatopathology
Granuloma annulare Dermatopathology
Hemangioma Dermatopathology
Invasive squamous cell carcinoma Dermatopathology
Verrucous carcinoma Dermatopathology
Kaposi sarcoma Dermatopathology
Lentigo maligna Dermatopathology
Lichen planus Dermatopathology
Lichen sclerosus Dermatopathology
Mastocytosis Dermatopathology
Melanoma Dermatopathology
Merkel cell carcinoma Dermatopathology
Mycosis fungoides Dermatopathology
Neurofibroma Dermatopathology
Neurothekeoma Dermatopathology
Nevus sebaceous Dermatopathology
Pemphigoid Dermatopathology
Pemphigus foliaceus Dermatopathology
Pigmented spindle cell nevus of Reed Dermatopathology
Pilar cyst Dermatopathology
Pilomatricoma Dermatopathology
Psoriasis Dermatopathology
Leukocytoclastic vasculitis Dermatopathology
Acute appendicitis Appendix
Adenocarcinoma in a villous adenoma Colon
Adenocarcinoma of the GE junction Esophagus/Stomach
Colorectal adenocarcinoma Colon
Amebiasis Colon
Barrett esophagus with low grade dysplasia Esophagus
Carcinoid tumour Esophagus
Celiac disease Duodenum
Chronic active gastritis with Helicobacter pylori Stomach
Colitis cystica profunda Colon
Collagenous colitis Colon
Cryptosporidium Colon
Diverticulitis Colon
Enterobius vermicularis appendix Appendix
Fundic gland polyp Stomach
Gastric adenocarcinoma Stomach
Gastric xanthoma Stomach
Giardiasis Duodenum
Gastrointestinal stromal tumour Gastrointestinal pathology
Hamartomatous polyp Gastrointestinal pathology
Herpes esophagitis Esophagus
Hyperplastic polyp Gastrointestinal pathology
Inflammatory pseudopolyp Gastrointestinal pathology
Intestinal metaplasia with dysplasia Gastrointestinal pathology
Intestinal spirochetosis Gastrointestinal pathology
Ischemic colitis Gastrointestinal pathology
Juvenile polyp Gastrointestinal pathology
Peutz-Jeghers polyp Gastrointestinal pathology Peutz-Jeghers syndrome
Leiomyoma of colon Colon
Leiomyoma of esophagus Esophagus
Meckel diverticulum Colon
Pseudomelanosis coli Colon
Necrotizing enteritis Colon
Pneumatosis intestinalis Colon
Pseudomembranous colitis Colon
Reactive gastropathy Stomach
Sessile serrated adenoma Gastrointestinal pathology
Traditional serrated adenoma Gastrointestinal pathology
Signet ring cell carcinoma Gastrointestinal pathology
Small bowel atresia Small bowel
Small bowel MAI Small bowel
Small cell carcinoma Gastrointestinal pathology
Solitary rectal ulcer Rectum
Strongyloides - appendix Appendix
Acute appendicitis with periappendicitis Appendix
Tubulovillous adenoma Gastrointestinal pathology
Ulcerative colitis Colon
Crohn's disease Gastrointestinal pathology
Whipple disease Duodenum
Small bowel neuroendocrine carcinoma Small bowel
Inflammatory fibroid polyp Gastrointestinal pathology
Adenomyoma of the gallbladder Gallbladder
Cholangiocarcinoma Gallbladder
Gallbladder adenocarcinoma Gallbladder
Cholesterolosis Gallbladder
Chronic cholecystitis Gallbladder
Alcoholic steatohepatitis Liver pathology
Bile duct atresia Liver pathology
Intrahepatic biliary atresia Liver pathology
Cholestatic hepatitis Liver pathology
Primary biliary cirrhosis Liver pathology
Cirrhosis Liver pathology
Micronodular cirrhosis with fatty changes Liver pathology
Fibrolamellar hepatocellular carcinoma Liver pathology
Hepatocellular carcinoma Liver pathology
Hepatic adenoma Liver pathology
Metastatic adenocarcinoma Liver pathology usu. colorectal carcinoma, DDx: pseudoglandular HCC, cholangiocarcinoma
Focal nodular hyperplasia Liver pathology
Fulminant hepatic necrosis Liver pathology
Hemochromatosis Liver pathology
Hepatoblastoma Liver pathology
Hydatid cyst of liver Liver pathology
Liver peliosis Liver pathology
Viral hepatitis Liver pathology
Giant cell hepatitis Liver pathology
Alpha-1 antitrypsin deficiency Liver pathology
Amyloidosis of the liver Liver pathology Amyloidosis
Hemangioma of the liver Liver pathology
Hemangioendothelioma of the liver Liver pathology Hemangioendothelioma
Islet cell tumour Pancreas
Mucinous cystadenoma of the pancreas Pancreas
Serous cystadenoma Pancreas
Serous microcystic adenoma of the pancreas Pancreas Von Hippel-Lindau disease
Invasive ductal carcinoma of the pancreas Pancreas
Solid pseudopapillary tumour Pancreas
Ganglioneuroblastoma Pediatric pathology
Ganglioneuroma Pediatric pathology
Neuroblastoma – adrenal Pediatric pathology
Wilms tumour Pediatric pathology
Hepatoblastoma Pediatric pathology
Medulloblastoma Pediatric pathology
Meconium ileus Pediatric pathology
Necrotizing enteritis Pediatric pathology
Alveolar rhabdomyosarcoma Pediatric pathology
Embryonal rhabdomyosarcoma Pediatric pathology
Sarcoma botryoides Pediatric pathology
Infantile capillary hemangioma Pediatric pathology
Choriocarcinoma Gynecologic pathology
Low-grade squamous intraepithelial lesion (LSIL) Gynecologic pathology
Adenocarcinoma in situ of the cervix (AIS) Gynecologic pathology
Arias-Stella reaction Gynecologic pathology
Atypical polypoid adenomyoma Gynecologic pathology
Ovarian serous borderline tumour Gynecologic pathology
Brenner tumour Gynecologic pathology
Condyloma acuminatum Gynecologic pathology
Carcinoma in situ of the cervix Gynecologic pathology
Clear cell carcinoma of the cervix Gynecologic pathology
Complete hydatidiform mole Gynecologic pathology
Partial hydatidiform mole Gynecologic pathology
Condyloma of the cervix Gynecologic pathology
Dysgerminoma Gynecologic pathology
Decidualized endometrium and chorionic villi Gynecologic pathology
Endometrioid endometrial adenocarcinoma Gynecologic pathology
Endometrial clear cell carcinoma Gynecologic pathology
Endometriosis Gynecologic pathology
Cystic endosalpingiosis Gynecologic pathology
Giant cell endometritis Gynecologic pathology
Granulosa cell tumour Gynecologic pathology
Immature teratoma Gynecologic pathology
Strumal carcinoid Gynecologic pathology
Uterine leiomyoma Gynecologic pathology
Uterine leiomyosarcoma Gynecologic pathology
Low-grade endometrial stromal sarcoma Gynecologic pathology
Menstrual endometrium Gynecologic pathology
Carcinosarcoma of the uterus Gynecologic pathology
Adenomatoid tumour of the uterus Gynecologic pathology
Mucinous cystadenoma of the ovary Gynecologic pathology
Mucinous-seromucinous low malignant potential tumour of the ovary Gynecologic pathology
Ovarian fibroma Gynecologic pathology
Peritoneal inclusion cyst Gynecologic pathology
Placental site trophoblastic tumour Gynecologic pathology
Proliferative type endometrium Gynecologic pathology
Ruptured tubal pregnancy Gynecologic pathology
Salpingitis isthmica nodosa Gynecologic pathology
Vulvar squamous cell carcinoma Gynecologic pathology
Secretory endometrium Gynecologic pathology
Serous carcinoma of the endometrium Gynecologic pathology
Serous cystadenoma of the ovary Gynecologic pathology
Serous LMP tumour Gynecologic pathology
Sertoli cell tumour Gynecologic pathology
Sertoli-Leydig cell tumour Gynecologic pathology
Simple hyperplasia of the endometrium Gynecologic pathology
Squamous cell carcinoma with adenocarcinoma in situ of the cervix Gynecologic pathology
Suppurative cervitis with decidualization Gynecologic pathology
High-grade squamous intraepithelial lesion (HSIL) Gynecologic pathology
Suppurative salpingitis Gynecologic pathology
Ovarian teratoma Gynecologic pathology
Tubal pregnancy Gynecologic pathology
Yolk sac tumour Gynecologic pathology
Extramammary Paget disease Gynecologic pathology
Atypical ductal hyperplasia Breast
Breast hyperplasia and papillomatosis Breast
Colloid carcinoma of the breast Breast
Ductal carcinoma in situ (DCIS) Breast
Micropapillary ductal carcinoma in situ Breast
Ductal carcinoma with cancerization of lobules Breast
Fibroadenoma Breast
Tubular adenoma of the breast Breast
Fibrocystic changes Breast
Florid epithelial hyperplasia Breast
Hemangioma of the breast Breast
Lobular carcinoma in situ Breast
Invasive ductal carcinoma of the breast Breast
Invasive lobular carcinoma Breast
Lactating adenoma Breast
Medullary carcinoma of the breast Breast
Mucinous carcinoma of the breast Breast
Multiple papillomas Breast
Paget disease of the nipple Breast
Papillary carcinoma of the breast Breast
Phyllodes tumour Breast
Sclerosing adenosis Breast
Fat necrosis of the breast Breast
Solitary fibrous tumour Soft tissue lesions
Nodular fasciitis Soft tissue lesions
Spindle cell lipoma Soft tissue lesions may be similar to Pleomorphic lipoma
Synovial sarcoma Soft tissue lesions
Angiofibroma Soft tissue lesions
Angiolipoma Soft tissue lesions
Schwannoma Soft tissue lesions
Dermatofibroma Soft tissue lesions
Elastofibroma Soft tissue lesions
Dermatofibrosarcoma protuberans Soft tissue lesions
Hemangiopericytoma Soft tissue lesions
Hemangioendothelioma of the liver Soft tissue lesions
Epithelioid hemangioendothelioma Soft tissue lesions
Intramuscular hemangioma Soft tissue lesions
Lymphangioma Soft tissue lesions
Glomus tumour Soft tissue lesions
Epithelioid sarcoma Soft tissue lesions
Alveolar rhabdomyosarcoma Soft tissue lesions
Embryonal rhabdomyosarcoma Soft tissue lesions
Botryoid rhabdomyosarcoma Soft tissue lesions
Alveolar soft part sarcoma Soft tissue lesions
Angiosarcoma Soft tissue lesions
Dedifferentiated liposarcoma Soft tissue lesions
Liposarcoma Soft tissue lesions
Chordoma Soft tissue lesions
Digital mucous cyst Soft tissue lesions
Leiomyoblastoma of stomach Soft tissue lesions
Desmoid tumour Soft tissue lesions
Palmar fibromatosis Soft tissue lesions
Lipoma of the spermatic cord Soft tissue lesions
Malignant peripheral nerve sheath tumour Soft tissue lesions
Eosinophilic granuloma of bone Bone
Plasmacytoma Bone
Fibrous dysplasia Bone
Giant cell tumour of bone Bone
Giant cell tumour of tendon sheath Bone usu. hand
Diffuse tenosynovial giant-cell tumour Bone pigmented villonodular synovitis
Osteosarcoma Bone
Osteoid osteoma Bone
Osteoblastoma Bone
Chondrosarcoma Bone
Chordoma Bone
Rheumatoid nodule Bone
Calcific tendonitis Bone
Gout Bone
Pseudogout Bone
Muscular dystrophy Bone
Myositis ossificans Bone
Angiolymphoid hyperplasia with eosinophilia Hematopathology
Burkitt lymphoma Hematopathology
Castleman disease Hematopathology
Diffuse large B cell lymphoma Hematopathology
Follicular lymphoma Hematopathology
Hodgkin lymphoma mixed cellularity type Hematopathology
Hodgkin lymphoma nodular sclerosis type Hematopathology
Metastatic small cell carcinoma to the lymph node Hematopathology
Multiple myeloma Hematopathology
Histiocytic necrotizing lymphadenitis (Kikuchi disease) Hematopathology
Plasmacytoma Hematopathology
Rosai-Dorfman disease Hematopathology
Extramedullary hematopoiesis (spleen) Hematopathology
Gaucher disease (spleen) Hematopathology
Hairy cell leukemia Hematopathology
Littoral cell angioma Hematopathology
Myeloid metaplasia of the spleen Hematopathology
Myelolipoma of the adrenal Hematopathology
MALToma Hematopathology
Myeloid sarcoma Hematopathology
Astrocytoma Neuropathology
Diffuse astrocytoma Neuropathology
Arteriovenous malformation Neuropathology
Ependymoma Neuropathology
Glioblastoma Neuropathology
Medulloblastoma Neuropathology
Meningioma Neuropathology
Metastatic carcinoma Neuropathology
Oligodendroglioma Neuropathology
Schwannoma Neuropathology
Subependymoma Neuropathology
Toxoplasmosis Neuropathology
Viral encephalitis Neuropathology
Metastatic melanoma Neuropathology
Acute myocardial infarction Cardiovascular pathology
Atrial myxoma Cardiovascular pathology
Cardiac amyloidosis Cardiovascular pathology
Fibrinous pericarditis Cardiovascular pathology
Arteriovenous malformation Cardiovascular pathology
Granulomatous myocarditis Cardiovascular pathology
Giant cell arteritis Cardiovascular pathology
Paraganglioma Miscellaneous
Inflammatory pseudotumour Miscellaneous
Adenomatoid tumour of the uterus Miscellaneous
Actinomycetes Miscellaneous
Amyloidosis of the liver Miscellaneous
Chorangioma Miscellaneous
Pseudogout Miscellaneous

See also