Silicone granuloma

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Silicone granuloma, also known as siliconoma,[1] is a foreign body granuloma elicited by silicone, which has been used in breast implants.

General

  • Presence is used as a basis for litigation.[2]

Microscopic

Features:

  • Foreign body-type granulomas with giant cells.
  • Translucent foreign material - seen with polarized light.

Images:

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Breast Nodule, Right Lateral, Excision:
     - Consistent with siliconoma; benign fibradipose tissue with 
       inflammation, and foreign body granulomas.
     - NEGATIVE for definite breast parenchyma.
     - NEGATIVE for evidence of malignancy.

See also

References

  1. Montserrat et al., "Silicone granuloma (siliconoma) secondary to liquid injectable silicone: Report of two cases," Available at: https://doi.org/10.1016/j.jaad.2011.11.869. Accessed on: 19 September 2018.
  2. Austad, ED. (Apr 2002). "Breast implant-related silicone granulomas: the literature and the litigation.". Plast Reconstr Surg 109 (5): 1724-30; discussion 1731-2. PMID 11932626.
  3. URL: http://granuloma.homestead.com/granuloma_foreignbody.html. Accessed on: 22 January 2012.
  4. URL: http://dermatology-s10.cdlib.org/147/letter/silicone/ricotti.html. Accessed on: 22 January 2012.