Herpes esophagitis

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Herpes esophagitis is an inflammation of the esophagus due to herpes simplex virus.

General

  • Usually immunodeficient.[1]

Etiology:

Gross/endoscopic

Features:

  • Ulcers with a "punched-out" appearance with a brown/red edge.

Images

www:

Microscopic

Features (3 Ms):

  • Moulding.
  • Multinucleation.
  • Margination of chromatin.

Images

IHC

  • HSV-1 +ve.[2]
    • Occasionally HSV-2 +ve.

See also

References

  1. Monsanto, P.; Almeida, N.; Cipriano, MA.; Gouveia, H.; Sofia, C. (Sep 2012). "Concomitant herpetic and eosinophilic esophagitis--a causality dilemma.". Acta Gastroenterol Belg 75 (3): 361-3. PMID 23082710.
  2. Canalejo Castrillero, E.; García Durán, F.; Cabello, N.; García Martínez, J. (Jul 2010). "Herpes esophagitis in healthy adults and adolescents: report of 3 cases and review of the literature.". Medicine (Baltimore) 89 (4): 204-10. doi:10.1097/MD.0b013e3181e949ed. PMID 20616659.