Chorangioma

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Chorangioma
Diagnosis in short

Chorangioma. H&E stain.

LM abundant capillaries surrounded by stroma
LM DDx chorangiosis, chorangiomatosis
Gross white or red lesion
Site placenta

Associated Dx +/-IUGR, +/-fetal hydrops - if large
Prevalence uncommon

Chorangioma is an uncommon pathology of the placenta that is similar to a hemangioma.

General

Epidemiology:

  • Often benign/insignificant; large lesions (>4 cm[1] or >5 cm[2]) or multiple lesions are significant.
  • May be association with:
  • Incidence: ~1 in 100 placentas.[1]

Gross

  • White lesions.
    • Occasionally red lesions.

Microscopic

Features:[1]

  • Mass of capillaries - key feature.
  • +/-High cellularity.
  • +/-Degenerative changes.

Notes:

Images

See also

References

  1. 1.0 1.1 1.2 1.3 1.4 Amer HZ, Heller DS (2010). "Chorangioma and related vascular lesions of the placenta--a review". Fetal Pediatr Pathol 29 (4): 199–206. doi:10.3109/15513815.2010.487009. PMID 20594143.
  2. Lež C, Fures R, Hrgovic Z, Belina S, Fajdic J, Münstedt K (2010). "Chorangioma placentae". Rare Tumors 2 (4): e67. doi:10.4081/rt.2010.e67. PMC 3019602. PMID 21234259. //www.ncbi.nlm.nih.gov/pmc/articles/PMC3019602/.