Nodular hidradenoma

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Nodular hidradenoma, also known as eccrine acrospiroma,[1] is a benign adnexal skin tumour.

General

  • Benign adnexal tumour.[2]

Gross

Typical locations:[1]

  • Scalp.
  • Face.
  • Trunk, anterior.

Microscopic

Features:[2]

  • Well-circumscribed dermal lesions with:
    • Back-to-back nests with a whorled appearance.
    • Spaces between cells.
    • Nuclei ovoid and centrally placed in the cell.
      • No nucleolus.
    • Cystic spaces with degenerated cells.

DDx:

Images

IHC

Features:[2]

  • CAM5.2 +ve.
  • AE1/AE3 +ve.
  • EMA +ve.
  • S100 -ve.
  • Desmin -ve.

See also

References

  1. 1.0 1.1 Punia, RP.; Garg, S.; Bal, A.; Mohan, H. (2008). "Pigmented nodular hidradenoma masquerading as nodular malignant melanoma.". Dermatol Online J 14 (1): 15. PMID 18319032.
  2. 2.0 2.1 2.2 Stratigos, AJ.; Olbricht, S.; Kwan, TH.; Bowers, KE. (Mar 1998). "Nodular hidradenoma. A report of three cases and review of the literature.". Dermatol Surg 24 (3): 387-91. PMID 9537017.