|Diagnosis in short|
Inflammatory polyp. H&E stain.
|LM||polypoid shape, inflammatory cells - esp. neutrophils|
|LM DDx||juvenile polyp, mucosal prolapse, adenomatous polyps|
|Site||colon, rectum, others|
|Clinical history||+/-inflammatory bowel disease|
|Clin. DDx||other types of polyps|
Inflammatory pseudopolyp is a benign polypoid lesion usually seen in the context of inflammatory bowel disease.
It is also referred to as inflammatory polyp.
- Not a true polyp.
- The label inflammatory pseudopolyp = inflammatory bowel disease (IBD).
- If there is no history of IBD... reconsider the diagnosis.
- Polypoid shape.
- Inflammation - esp. neutrophils - key feature.
- No nuclear atypia.
- May have focal nuclear hyperchromasia and nuclear enlargement.
- No dilated glands.
SIGMOID COLON POLYP, PERI-DIVERTICULAR, BIOPSY: - INFLAMMATORY PSEUDOPOLYP.
POLYP, DESCENDING COLON, BIOPSY: - INFLAMED POLYPOID FRAGMENT OF COLORECTAL-TYPE MUCOSA. -- NEGATIVE FOR DYSPLASIA.
Polyp, Sigmoid Colon, Polypectomy: - Colonic mucosa with ulceration, acute inflammation and granulation tissue. - NEGATIVE for dysplasia. Comment: This may represent a polyp seen in the context of diverticular disease. Other considerations include ischemia, idiopathic inflammation and infections. Clinical correlation is suggested.
POLYP (AT EDGE OF DIVERTICULUM), SIGMOID COLON, POLYPECTOMY: - GRANULATION TISSUE AND SCANT BENIGN EPITHELIUM. - NO EVIDENCE OF DYSPLASIA.
The sections show a fragment of colorectal mucosa with focal ulceration, acute inflammation and a well-vascularized stroma with plump stromal cells. Occasional stromal cells have nuclear hyperchromasia.
The sections show a fragment of tissue with scant benign epithelium, acute and chronic inflammation (neutrophils and plasma cells predominantly), abundant blood vessels with reactive endothelial cells and plump stromal cells. Occasional stromal cells have nuclear hyperchromasia but do not show significant atypia.