Difference between revisions of "Epithelioid cell lesions"

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(merge in ''Large epithelioid tumours'')
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==Differential diagnosis==
==Differential diagnosis==
A short DDx:
===A short DDx===
*Carcinoma (primary and metastatic).
*Carcinoma (primary and metastatic).
*[[Malignant melanoma]].
*[[Malignant melanoma]].
*Sarcoma.
*Sarcoma.


===Large epithelioid tumours===
====Epithelioid sarcomas====
An exhaustive [[DDx]] for a ''large epithelioid tumour'' is in ''[[large epithelioid tumours]]''.
 
==Epithelioid sarcomas==
All rules are made to be broken... some epithelioid lesions are sarcomas:<ref name=pmid19664495>{{cite journal |author=Dei Tos AP, Wagner AJ, Modena P, Comandone A, Leyvraz S |title=Epithelioid soft tissue tumors |journal=Semin. Oncol. |volume=36 |issue=4 |pages=347–57 |year=2009 |month=August |pmid=19664495 |doi=10.1053/j.seminoncol.2009.06.005 |url=}}</ref>
All rules are made to be broken... some epithelioid lesions are sarcomas:<ref name=pmid19664495>{{cite journal |author=Dei Tos AP, Wagner AJ, Modena P, Comandone A, Leyvraz S |title=Epithelioid soft tissue tumors |journal=Semin. Oncol. |volume=36 |issue=4 |pages=347–57 |year=2009 |month=August |pmid=19664495 |doi=10.1053/j.seminoncol.2009.06.005 |url=}}</ref>
*[[Epithelioid sarcoma]].
*[[Epithelioid sarcoma]].
Line 24: Line 21:


Note:
Note:
*A more complete list is in ''[[large epithelioid tumours]]''.
*A more complete list is below.
 
===Large epithelioid tumours===
The following is an exhaustive [[DDx]] for a ''large epithelioid tumour''.
 
{| class="wikitable sortable"
! Tumour
! Group
! Notes/comments
|-
| [[Melanoma]]
| Miscellaneous
| 
|-
| [[PEComa]]
| Miscellaneous
| esp. [[epithelioid angiomyolipoma]]
|-
| [[Perivascular epithelioid cell sarcoma]]
| Miscellaneous
| type of PEComa, looks like clear cell carcinoma<ref name=pmid11406657>{{Cite journal | last1 = Bonetti| first1 = F.| last2 = Martignoni| first2 = G.| last3 = Colato| first3 = C.| last4 = Manfrin| first4 = E.| last5 = Gambacorta| first5 = M.| last6 = Faleri| first6 = M.| last7 = Bacchi| first7 = C.| last8 = Sin| first8 = VC.| last9 = Wong| first9 = NL.| title = Abdominopelvic sarcoma of perivascular epithelioid cells. Report of four cases in young women, one with tuberous sclerosis.| journal = Mod Pathol| volume = 14| issue = 6| pages = 563-8| month = Jun| year = 2001| doi = 10.1038/modpathol.3880351| PMID = 11406657 }}</ref>
|-
| [[Paraganglioma-like dermal melanocytic tumour]]
| Miscellaneous
| <ref name=pmid15577676>{{Cite journal | last1 = Deyrup| first1 = AT.| last2 = Althof| first2 = P.| last3 = Zhou| first3 = M.| last4 = Morgan| first4 = M.| last5 = Solomon| first5 = AR.| last6 = Bridge| first6 = JA.| last7 = Weiss| first7 = SW.| title = Paraganglioma-like dermal melanocytic tumor: a unique entity distinct from cellular blue nevus, clear cell sarcoma, and cutaneous melanoma.| journal = Am J Surg Pathol| volume = 28| issue = 12| pages = 1579-86| month = Dec| year = 2004| doi = | PMID = 15577676 }}</ref>
|-
| [[Carcinoma]]
| Epithelial tumours
|HCC and adrenal cortical carcinoma, often AE1/AE3 -ve
|-
| [[Hepatoid Adenocarcinoma]]
| Epithelial tumours
| 
|-
| [[Malignant mixed Muellerian tumour]]
| Epithelial tumours
| 
|-
| [[Myoepithelial carcinoma]]
| Epithelial tumours
| 
|-
| [[Myoepithelioma of soft tissue]]
| Epithelial tumours
| may mimic [[extraskeletal myxoid chondrosarcoma]] or proximal variant of [[epithelial sarcoma]]
|-
| [[Acinar cell carcinoma]]
| Epithelial tumours
| 
|-
| [[Neuroendocrine carcinoma]]
| Epithelial tumours
| may have a rhabdoid morphology<ref name=pmid12717248>{{Cite journal | last1 = Perez-Montiel| first1 = MD.| last2 = Frankel| first2 = WL.| last3 = Suster| first3 = S.| title = Neuroendocrine carcinomas of the pancreas with 'Rhabdoid' features.| journal = Am J Surg Pathol| volume = 27| issue = 5| pages = 642-9| month = May| year = 2003| doi = | PMID = 12717248 }}</ref>
|-
| [[Medullary thyroid carcinoma]]
| Epithelial tumours
| 
|-
| [[Thymoma]]
| Epithelial tumours
| 
|-
| [[Cutaneous myoepithelioma]]
| Epithelial tumours
| <ref name=pmid11224605>{{Cite journal | last1 = Kutzner| first1 = H.| last2 = Mentzel| first2 = T.| last3 = Kaddu| first3 = S.| last4 = Soares| first4 = LM.| last5 = Sangueza| first5 = OP.| last6 = Requena| first6 = L.| title = Cutaneous myoepithelioma: an under-recognized cutaneous neoplasm composed of myoepithelial cells.| journal = Am J Surg Pathol| volume = 25| issue = 3| pages = 348-55| month = Mar| year = 2001| doi = | PMID = 11224605 }}</ref>
|-
| Cutaneous adnexal tumours ([[spiradenoma]], [[acrospiroma]])
| Epithelial tumours
| 
|-
| [[Hyaline-rich chondroid syringoma]]
| Epithelial tumours
| 
|-
| [[Hurthle cell tumour]]
| Epithelial tumours
| 
|-
| [[Mesothelioma]]
| Epithelial tumours
| "lymphohistiocytoid" variant
|-
| [[Seminoma]]
| Germ- cell / Sex-Cord Stromal
| 
|-
| [[Embryonal carcinoma]]
| Germ- cell / Sex-Cord Stromal
| 
|-
| [[Yolk sac tumour]]
| Germ- cell / Sex-Cord Stromal
| consider hepatoid variant
|-
| [[Choriocarcinoma]]
| Germ- cell / Sex-Cord Stromal
| 
|-
| [[Epithelioid trophoblastic tumour]]
| Germ- cell / Sex-Cord Stromal
| 
|-
| [[Granulosa cell tumour]]
| Germ- cell / Sex-Cord Stromal
| 
|-
| [[Endometrial stromal sarcoma]]
| Germ- cell / Sex-Cord Stromal
| high grade
|-
| [[Lipid Cell tumour of ovary]]
| Germ- cell / Sex-Cord Stromal
| 
|-
| [[Sertoli cell tumour]]
| Germ- cell / Sex-Cord Stromal
| also [[Sertoli-Leydig cell tumour]] 
|-
| [[Leydig cell tumour]]
| Germ- cell / Sex-Cord Stromal
| also [[Sertoli-Leydig cell tumour]]
|-
| [[Epithelioid trophoblastic tumour]]
| Germ- cell / Sex-Cord Stromal
| <ref name=pmid10571512>{{Cite journal | last1 = Hamazaki| first1 = S.| last2 = Nakamoto| first2 = S.| last3 = Okino| first3 = T.| last4 = Tsukayama| first4 = C.| last5 = Mori| first5 = M.| last6 = Taguchi| first6 = K.| last7 = Okada| first7 = S.| title = Epithelioid trophoblastic tumor: morphological and immunohistochemical study of three lung lesions.| journal = Hum Pathol| volume = 30| issue = 11| pages = 1321-7| month = Nov| year = 1999| doi = | PMID = 10571512 }}</ref><ref name=pmid9808132>{{Cite journal | last1 = Shih| first1 = IM.| last2 = Kurman| first2 = RJ.| title = Epithelioid trophoblastic tumor: a neoplasm distinct from choriocarcinoma and placental site trophoblastic tumor simulating carcinoma.| journal = Am J Surg Pathol| volume = 22| issue = 11| pages = 1393-403| month = Nov| year = 1998| doi = | PMID = 9808132 }}</ref>
|-
| [[Placental site trophoblastic tumour]]
| Germ- cell / Sex-Cord Stromal
|(USCAP04, Gyn spec conf, case 3, vaginal
|-
| [[Testicular tumour of the adrenogenital syndrome]]
| Germ- cell / Sex-Cord Stromal
| Inhibin -ve, dark brown-green-black, similar to Leydig tumour
|-
| [[Extrauterine lesion of intermediate trophoblast]]
| Germ- cell / Sex-Cord Stromal
| very rare
|-
| [[Lymphoma]]
| Hematolymphoid / Histiocytic tumours
| 
|-
| [[Hodgkin's lymphoma]]
| Hematolymphoid / Histiocytic tumours
| syncytial or lymphocyte-depleted
|-
| [[Extramedullary monoblastic leukemia]]
| Hematolymphoid / Histiocytic tumours
| 
|-
| [[Histiocytic sarcoma]]
| Hematolymphoid / Histiocytic tumours
| "True" histiocytic lymphoma
|-
| [[Langerhans cell histiocytosis ]]
| Hematolymphoid / Histiocytic tumours
| 
|-
| [[Rosai-Dorfman disease]]
| Hematolymphoid / Histiocytic tumours
| 
|-
| [[Crystal-storing histiocytosis]]
| Hematolymphoid / Histiocytic tumours
| 
|-
| [[Erdheim-Chester disease]]
| Hematolymphoid / Histiocytic tumours
| foamy histiocytes
|-
| [[Rhinoscleroma]]
| Hematolymphoid / Histiocytic tumours
| foamy histiocytes and chronic inflammation
|-
| [[Granuloma annulare]]
| Hematolymphoid / Histiocytic tumours
| 
|-
| [[Anaplastic myeloma]]
| Hematolymphoid / Histiocytic tumours
| 
|-
| [[Extramedullary myeloid leukemia]]
| Hematolymphoid / Histiocytic tumours
| 
|-
| [[Extramedullary lymphoid leukemia]]
| Hematolymphoid / Histiocytic tumours
| 
|-
| [[Extramedullary megakaryoblastic leukemia]]
| Hematolymphoid / Histiocytic tumours
| 
|-
| [[Erythroleukemia]]
| Hematolymphoid / Histiocytic tumours
| may be EMA +ve
|-
| [[Juvenile xanthogranuloma]]
| Hematolymphoid / Histiocytic tumours
| 
|-
| [[Paraganglioma]]
| Neural - Neuroendocrine - Neuraxis Tumours
| also [[pheochromocytoma]]
|-
| [[High grade olfactory neuroblastoma]]
| Neural - Neuroendocrine - Neuraxis Tumours
| 
|-
| [[Epithelioid MPNST]]
| Neural - Neuroendocrine - Neuraxis Tumours
| reported to have focal melanocytic differentiation in some cases{{fact}}
|-
| [[Glioblastoma]]
| Neural - Neuroendocrine - Neuraxis Tumours
| 
|-
| [[Epithelioid schwannoma / neurofibroma]]
| Neural - Neuroendocrine - Neuraxis Tumours
| 
|-
| [[Benign epithelioid nerve sheath tumour]]
| Neural - Neuroendocrine - Neuraxis Tumours
| 
|-
| [[Chordoma]]
| Neural - Neuroendocrine - Neuraxis Tumours
| 
|-
| [[Meningioma]]
| Neural - Neuroendocrine - Neuraxis Tumours
| [[chordoid meningioma]]
|-
| [[Parachordoma]]
| Neural - Neuroendocrine - Neuraxis Tumours
| <ref name=pmid10478665>{{Cite journal | last1 = Folpe| first1 = AL.| last2 = Agoff| first2 = SN.| last3 = Willis| first3 = J.| last4 = Weiss| first4 = SW.| title = Parachordoma is immunohistochemically and cytogenetically distinct from axial chordoma and extraskeletal myxoid chondrosarcoma.| journal = Am J Surg Pathol| volume = 23| issue = 9| pages = 1059-67| month = Sep| year = 1999| doi = | PMID = 10478665 }}</ref>
|-
| [[Ependymoma]]
| Neural - Neuroendocrine - Neuraxis Tumours
| 
|-
| [[Epithelioid perineurioma]]
| Neural - Neuroendocrine - Neuraxis Tumours
| 
|-
| [[Hemangioblastoma]]
| Neural - Neuroendocrine - Neuraxis Tumours
| may be extraneural
|-
| [[Rhabdoid tumour]]
| Neural - Neuroendocrine - Neuraxis Tumours
| INI1 -ve
|-
| [[Mucosal epithelioid nerve sheath tumour]]
| Neural - Neuroendocrine - Neuraxis Tumours
| 
|-
| [[Neurothekeoma]]
| Neural - Neuroendocrine - Neuraxis Tumours
| 
|-
| [[Pleomorphic rhabdomyosarcoma]]
| Muscle-related tumours
| 
|-
| [[Epithelioid leiomyosarcoma]]
| Muscle-related tumours
| 
|-
| [[Epithelioid glomus tumour]]
| Muscle-related tumours
| 
|-
| [[Granular cell tumour]]
| Muscle-related tumours
| neural, non-neural types
|-
| [[Rhabdomyoma]]
| Muscle-related tumours
| 
|-
| [[Myopericytoma]]
| Muscle-related tumours
| <ref name=pmid16330949>{{Cite journal | last1 = Mentzel| first1 = T.| last2 = Dei Tos| first2 = AP.| last3 = Sapi| first3 = Z.| last4 = Kutzner| first4 = H.| title = Myopericytoma of skin and soft tissues: clinicopathologic and immunohistochemical study of 54 cases.| journal = Am J Surg Pathol| volume = 30| issue = 1| pages = 104-13| month = Jan| year = 2006| doi = | PMID = 16330949 }}</ref>
|-
| [[Epithelioid angiosarcoma]]
| Vascular tumours
| 
|-
| [[Epithelioid hemangioendothelioma]]
| Vascular tumours
| 
|-
| [[Epith sarcoma-like hemangioendothelioma ]]
| Vascular tumours
| 
|-
| [[Composite hemangioendothelioma]]
| Vascular tumours
| 
|-
| [[Hemangiopericytoma]]
| Vascular tumours
| 
|-
| [[Cutaneous epithelioid angiomatous nodule ]]
| Vascular tumours
| 
|-
| [[Bacillary angiomatosis ]]
| Vascular tumours
| 
|-
| [[Malignant pigmented villonodular synovitis]]
| Hematolymphoid / Histiocytic tumours
| 
|-
| [[Multicentric Reticulohistiocytosis]]
| Hematolymphoid / Histiocytic tumours
| 
|-
| [[Follicular dendritic cell sarcoma]]
| Hematolymphoid / Histiocytic tumours
| 
|-
| [[Interdigitating reticulum cell sarcoma]]
| Hematolymphoid / Histiocytic tumours
|S-100 +ve
|-
| [[Diffuse type tenosynovial giant cell tumour]]
| Hematolymphoid / Histiocytic tumours
| 
|-
| [[Malakoplakia]]
| Hematolymphoid / Histiocytic tumours
| 
|-
| [[Kikuchi's disease]]
| Hematolymphoid / Histiocytic tumours
| 
|-
| [[Xanthogranuloma]]
| Hematolymphoid / Histiocytic tumours
| 
|-
| [[Epithelioid sarcoma]]
| Miscellaneous mesencchymal tumours
| especially proximal variant
|-
| [[Synovial sarcoma]]
| Miscellaneous mesencchymal tumours
| poorly differentiated
|-
| [[Alveolar soft part sarcoma]]
| Miscellaneous mesencchymal tumours
| TFE3 +ve
|-
| [[Gastrointestinal stromal tumour]]
| Miscellaneous mesencchymal tumours
| 
|-
| [[Round cell liposarcoma]]
| Miscellaneous mesencchymal tumours
| 
|-
| [[Dedifferentiated liposarcoma]]
| Miscellaneous mesencchymal tumours
| 
|-
| [[Epithelioid variant of pleomorphic liposarcoma]]
| Miscellaneous mesencchymal tumours
| 
|-
| [[Polyphenotypic small cell tumour]]
| Miscellaneous mesencchymal tumours
| 
|-
| [[Ewing Sarcoma / PNET, large cell type]]
| Miscellaneous mesencchymal tumours
| 
|-
| [[Epithelioid fibrous histiocytoma]]
| Myofibroblastic - fibroblastic tumours
| 
|-
| [[Inflammatory malignant fibrous histiocytoma]]
| Myofibroblastic - fibroblastic tumours
| 
|-
| [[Sclerosing epithelioid fibrosarcoma]]
| Myofibroblastic - fibroblastic tumours
| 
|-
| [[Epithlelioid myofibroblastoma]]
| Myofibroblastic - fibroblastic tumours  
| 
|-
| [[Angiomatoid malignant fibrous histiocytoma]]  
| Myofibroblastic - fibroblastic tumours
| 
|-
| [[Inflammatory myxohyaline tumour of distal extremities with virocyte or Reed-Sternberg like cells]]
| Myofibroblastic - fibroblastic tumours
| 
|-
| [[Acral myxoinflammatory fibroblastic sarcoma]]
| Myofibroblastic - fibroblastic tumours
| 
|-
| [[Angiomyofibroblastoma]]
| Myofibroblastic - fibroblastic tumours
| 
|-
| [[Epithelioid osteosarcoma]]
| Chondro-osseous tumours
| 
|-
| [[Extraskeletal myxoid chondrosarcoma, high grade]]
| Chondro-osseous tumours
| 
|-
| [[Epithelioid multinodular osteoblastoma]]
| Chondro-osseous tumours
| may mimic [[osteosarcoma]]<ref name=pmid17667552>{{Cite journal | last1 = Zon Filippi| first1 = R.| last2 = Swee| first2 = RG.| last3 = Krishnan Unni| first3 = K.| title = Epithelioid multinodular osteoblastoma: a clinicopathologic analysis of 26 cases.| journal = Am J Surg Pathol| volume = 31| issue = 8| pages = 1265-8| month = Aug| year = 2007| doi = 10.1097/PAS.0b013e31803402e7| PMID = 17667552 }}</ref>
|-
| [[Radiation effect]]
| Miscellaneous
| 
|-
|}


==See also==
==See also==
*[[Spindle cell lesions]].
*[[Spindle cell lesions]].
*[[Large epithelioid tumours]].
*[[Basics]].
*[[Pleomorphic tumours]].


==References==
==References==
{{Reflist|1}}
{{Reflist|2}}


[[Category:Basics]]
[[Category:Basics]]

Revision as of 02:37, 7 October 2013

Epithelioid cell lesions are very common in pathology. Malignant epithelioid lesions are usually a carcinoma.

Differential diagnosis

A short DDx

Epithelioid sarcomas

All rules are made to be broken... some epithelioid lesions are sarcomas:[1]

Others:

Note:

  • A more complete list is below.

Large epithelioid tumours

The following is an exhaustive DDx for a large epithelioid tumour.

Tumour Group Notes/comments
Melanoma Miscellaneous
PEComa Miscellaneous esp. epithelioid angiomyolipoma
Perivascular epithelioid cell sarcoma Miscellaneous type of PEComa, looks like clear cell carcinoma[2]
Paraganglioma-like dermal melanocytic tumour Miscellaneous [3]
Carcinoma Epithelial tumours HCC and adrenal cortical carcinoma, often AE1/AE3 -ve
Hepatoid Adenocarcinoma Epithelial tumours
Malignant mixed Muellerian tumour Epithelial tumours
Myoepithelial carcinoma Epithelial tumours
Myoepithelioma of soft tissue Epithelial tumours may mimic extraskeletal myxoid chondrosarcoma or proximal variant of epithelial sarcoma
Acinar cell carcinoma Epithelial tumours
Neuroendocrine carcinoma Epithelial tumours may have a rhabdoid morphology[4]
Medullary thyroid carcinoma Epithelial tumours
Thymoma Epithelial tumours
Cutaneous myoepithelioma Epithelial tumours [5]
Cutaneous adnexal tumours (spiradenoma, acrospiroma) Epithelial tumours
Hyaline-rich chondroid syringoma Epithelial tumours
Hurthle cell tumour Epithelial tumours
Mesothelioma Epithelial tumours "lymphohistiocytoid" variant
Seminoma Germ- cell / Sex-Cord Stromal
Embryonal carcinoma Germ- cell / Sex-Cord Stromal
Yolk sac tumour Germ- cell / Sex-Cord Stromal consider hepatoid variant
Choriocarcinoma Germ- cell / Sex-Cord Stromal
Epithelioid trophoblastic tumour Germ- cell / Sex-Cord Stromal
Granulosa cell tumour Germ- cell / Sex-Cord Stromal
Endometrial stromal sarcoma Germ- cell / Sex-Cord Stromal high grade
Lipid Cell tumour of ovary Germ- cell / Sex-Cord Stromal
Sertoli cell tumour Germ- cell / Sex-Cord Stromal also Sertoli-Leydig cell tumour
Leydig cell tumour Germ- cell / Sex-Cord Stromal also Sertoli-Leydig cell tumour
Epithelioid trophoblastic tumour Germ- cell / Sex-Cord Stromal [6][7]
Placental site trophoblastic tumour Germ- cell / Sex-Cord Stromal (USCAP04, Gyn spec conf, case 3, vaginal
Testicular tumour of the adrenogenital syndrome Germ- cell / Sex-Cord Stromal Inhibin -ve, dark brown-green-black, similar to Leydig tumour
Extrauterine lesion of intermediate trophoblast Germ- cell / Sex-Cord Stromal very rare
Lymphoma Hematolymphoid / Histiocytic tumours
Hodgkin's lymphoma Hematolymphoid / Histiocytic tumours syncytial or lymphocyte-depleted
Extramedullary monoblastic leukemia Hematolymphoid / Histiocytic tumours
Histiocytic sarcoma Hematolymphoid / Histiocytic tumours "True" histiocytic lymphoma
Langerhans cell histiocytosis Hematolymphoid / Histiocytic tumours
Rosai-Dorfman disease Hematolymphoid / Histiocytic tumours
Crystal-storing histiocytosis Hematolymphoid / Histiocytic tumours
Erdheim-Chester disease Hematolymphoid / Histiocytic tumours foamy histiocytes
Rhinoscleroma Hematolymphoid / Histiocytic tumours foamy histiocytes and chronic inflammation
Granuloma annulare Hematolymphoid / Histiocytic tumours
Anaplastic myeloma Hematolymphoid / Histiocytic tumours
Extramedullary myeloid leukemia Hematolymphoid / Histiocytic tumours
Extramedullary lymphoid leukemia Hematolymphoid / Histiocytic tumours
Extramedullary megakaryoblastic leukemia Hematolymphoid / Histiocytic tumours
Erythroleukemia Hematolymphoid / Histiocytic tumours may be EMA +ve
Juvenile xanthogranuloma Hematolymphoid / Histiocytic tumours
Paraganglioma Neural - Neuroendocrine - Neuraxis Tumours also pheochromocytoma
High grade olfactory neuroblastoma Neural - Neuroendocrine - Neuraxis Tumours
Epithelioid MPNST Neural - Neuroendocrine - Neuraxis Tumours reported to have focal melanocytic differentiation in some cases[citation needed]
Glioblastoma Neural - Neuroendocrine - Neuraxis Tumours
Epithelioid schwannoma / neurofibroma Neural - Neuroendocrine - Neuraxis Tumours
Benign epithelioid nerve sheath tumour Neural - Neuroendocrine - Neuraxis Tumours
Chordoma Neural - Neuroendocrine - Neuraxis Tumours
Meningioma Neural - Neuroendocrine - Neuraxis Tumours chordoid meningioma
Parachordoma Neural - Neuroendocrine - Neuraxis Tumours [8]
Ependymoma Neural - Neuroendocrine - Neuraxis Tumours
Epithelioid perineurioma Neural - Neuroendocrine - Neuraxis Tumours
Hemangioblastoma Neural - Neuroendocrine - Neuraxis Tumours may be extraneural
Rhabdoid tumour Neural - Neuroendocrine - Neuraxis Tumours INI1 -ve
Mucosal epithelioid nerve sheath tumour Neural - Neuroendocrine - Neuraxis Tumours
Neurothekeoma Neural - Neuroendocrine - Neuraxis Tumours
Pleomorphic rhabdomyosarcoma Muscle-related tumours
Epithelioid leiomyosarcoma Muscle-related tumours
Epithelioid glomus tumour Muscle-related tumours
Granular cell tumour Muscle-related tumours neural, non-neural types
Rhabdomyoma Muscle-related tumours
Myopericytoma Muscle-related tumours [9]
Epithelioid angiosarcoma Vascular tumours
Epithelioid hemangioendothelioma Vascular tumours
Epith sarcoma-like hemangioendothelioma Vascular tumours
Composite hemangioendothelioma Vascular tumours
Hemangiopericytoma Vascular tumours
Cutaneous epithelioid angiomatous nodule Vascular tumours
Bacillary angiomatosis Vascular tumours
Malignant pigmented villonodular synovitis Hematolymphoid / Histiocytic tumours
Multicentric Reticulohistiocytosis Hematolymphoid / Histiocytic tumours
Follicular dendritic cell sarcoma Hematolymphoid / Histiocytic tumours
Interdigitating reticulum cell sarcoma Hematolymphoid / Histiocytic tumours S-100 +ve
Diffuse type tenosynovial giant cell tumour Hematolymphoid / Histiocytic tumours
Malakoplakia Hematolymphoid / Histiocytic tumours
Kikuchi's disease Hematolymphoid / Histiocytic tumours
Xanthogranuloma Hematolymphoid / Histiocytic tumours
Epithelioid sarcoma Miscellaneous mesencchymal tumours especially proximal variant
Synovial sarcoma Miscellaneous mesencchymal tumours poorly differentiated
Alveolar soft part sarcoma Miscellaneous mesencchymal tumours TFE3 +ve
Gastrointestinal stromal tumour Miscellaneous mesencchymal tumours
Round cell liposarcoma Miscellaneous mesencchymal tumours
Dedifferentiated liposarcoma Miscellaneous mesencchymal tumours
Epithelioid variant of pleomorphic liposarcoma Miscellaneous mesencchymal tumours
Polyphenotypic small cell tumour Miscellaneous mesencchymal tumours
Ewing Sarcoma / PNET, large cell type Miscellaneous mesencchymal tumours
Epithelioid fibrous histiocytoma Myofibroblastic - fibroblastic tumours
Inflammatory malignant fibrous histiocytoma Myofibroblastic - fibroblastic tumours
Sclerosing epithelioid fibrosarcoma Myofibroblastic - fibroblastic tumours
Epithlelioid myofibroblastoma Myofibroblastic - fibroblastic tumours
Angiomatoid malignant fibrous histiocytoma Myofibroblastic - fibroblastic tumours
Inflammatory myxohyaline tumour of distal extremities with virocyte or Reed-Sternberg like cells Myofibroblastic - fibroblastic tumours
Acral myxoinflammatory fibroblastic sarcoma Myofibroblastic - fibroblastic tumours
Angiomyofibroblastoma Myofibroblastic - fibroblastic tumours
Epithelioid osteosarcoma Chondro-osseous tumours
Extraskeletal myxoid chondrosarcoma, high grade Chondro-osseous tumours
Epithelioid multinodular osteoblastoma Chondro-osseous tumours may mimic osteosarcoma[10]
Radiation effect Miscellaneous

See also

References

  1. ↑ Dei Tos AP, Wagner AJ, Modena P, Comandone A, Leyvraz S (August 2009). "Epithelioid soft tissue tumors". Semin. Oncol. 36 (4): 347–57. doi:10.1053/j.seminoncol.2009.06.005. PMID 19664495.
  2. ↑ Bonetti, F.; Martignoni, G.; Colato, C.; Manfrin, E.; Gambacorta, M.; Faleri, M.; Bacchi, C.; Sin, VC. et al. (Jun 2001). "Abdominopelvic sarcoma of perivascular epithelioid cells. Report of four cases in young women, one with tuberous sclerosis.". Mod Pathol 14 (6): 563-8. doi:10.1038/modpathol.3880351. PMID 11406657.
  3. ↑ Deyrup, AT.; Althof, P.; Zhou, M.; Morgan, M.; Solomon, AR.; Bridge, JA.; Weiss, SW. (Dec 2004). "Paraganglioma-like dermal melanocytic tumor: a unique entity distinct from cellular blue nevus, clear cell sarcoma, and cutaneous melanoma.". Am J Surg Pathol 28 (12): 1579-86. PMID 15577676.
  4. ↑ Perez-Montiel, MD.; Frankel, WL.; Suster, S. (May 2003). "Neuroendocrine carcinomas of the pancreas with 'Rhabdoid' features.". Am J Surg Pathol 27 (5): 642-9. PMID 12717248.
  5. ↑ Kutzner, H.; Mentzel, T.; Kaddu, S.; Soares, LM.; Sangueza, OP.; Requena, L. (Mar 2001). "Cutaneous myoepithelioma: an under-recognized cutaneous neoplasm composed of myoepithelial cells.". Am J Surg Pathol 25 (3): 348-55. PMID 11224605.
  6. ↑ Hamazaki, S.; Nakamoto, S.; Okino, T.; Tsukayama, C.; Mori, M.; Taguchi, K.; Okada, S. (Nov 1999). "Epithelioid trophoblastic tumor: morphological and immunohistochemical study of three lung lesions.". Hum Pathol 30 (11): 1321-7. PMID 10571512.
  7. ↑ Shih, IM.; Kurman, RJ. (Nov 1998). "Epithelioid trophoblastic tumor: a neoplasm distinct from choriocarcinoma and placental site trophoblastic tumor simulating carcinoma.". Am J Surg Pathol 22 (11): 1393-403. PMID 9808132.
  8. ↑ Folpe, AL.; Agoff, SN.; Willis, J.; Weiss, SW. (Sep 1999). "Parachordoma is immunohistochemically and cytogenetically distinct from axial chordoma and extraskeletal myxoid chondrosarcoma.". Am J Surg Pathol 23 (9): 1059-67. PMID 10478665.
  9. ↑ Mentzel, T.; Dei Tos, AP.; Sapi, Z.; Kutzner, H. (Jan 2006). "Myopericytoma of skin and soft tissues: clinicopathologic and immunohistochemical study of 54 cases.". Am J Surg Pathol 30 (1): 104-13. PMID 16330949.
  10. ↑ Zon Filippi, R.; Swee, RG.; Krishnan Unni, K. (Aug 2007). "Epithelioid multinodular osteoblastoma: a clinicopathologic analysis of 26 cases.". Am J Surg Pathol 31 (8): 1265-8. doi:10.1097/PAS.0b013e31803402e7. PMID 17667552.
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