Epithelioid cell lesions

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An tumour with an epithelioid morphology (epithelioid sarcoma). H&E stain.

Epithelioid cell lesions are very common in pathology. Malignant epithelioid lesions are most often carcinomas... but may be a large number different tumours.


Broadly, epithelioid lesions are split into:

General differential diagnosis

A short DDx:

Epithelioid sarcomas

All rules are made to be broken... some epithelioid lesions are sarcomas:[1]



See also


  1. Dei Tos AP, Wagner AJ, Modena P, Comandone A, Leyvraz S (August 2009). "Epithelioid soft tissue tumors". Semin. Oncol. 36 (4): 347–57. doi:10.1053/j.seminoncol.2009.06.005. PMID 19664495.