Difference between revisions of "Case 116"
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Low magnification. H&E stain.
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[[Image: Leiomyoma with changes secondary to tranexamic acid treatment low magnification.jpg |500px|link=|center|]] | [[Image: Leiomyoma with changes secondary to tranexamic acid treatment low magnification.jpg |500px|link=|center|]] | ||
<center>Low magnification. [[H&E stain]].</center> | <center>Low magnification. [[H&E stain]].</center> | ||
{{hidden|High magnification|[[Image: Leiomyoma with changes secondary to tranexamic acid treatment high magnification.jpg |500px|link=|center|]] | {{hidden|High magnification|[[Image: Leiomyoma with changes secondary to tranexamic acid treatment high magnification.jpg |500px|link=|center|]] | ||
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===Differential diagnosis=== | ===Differential diagnosis=== | ||
{{hidden|Differential diagnosis|<center>[[Smooth muscle tumour of uncertain malignant potential]] (STUMP), [[uterine leiomyosarcoma]] </center>}} | {{hidden|Differential diagnosis|<center>[[Smooth muscle tumour of uncertain malignant potential]] (STUMP), [[uterine leiomyosarcoma]]</center>}} | ||
===Additional tests=== | ===Additional tests=== | ||
====More history==== | ====More history==== | ||
{{hidden|More history|<center>Patient had received lysteda for control of bleeding </center>}} | {{hidden|More history|<center>Patient had received lysteda for control of bleeding.</center>}} | ||
====Ask a colleague==== | ====Ask a colleague==== | ||
{{hidden|Ask a colleague|<center> | {{hidden|Ask a colleague|<center>Did you check the history? I wonder whether this could be drug effect.</center>}} | ||
====Stains==== | ====Stains==== | ||
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===Diagnosis=== | ===Diagnosis=== | ||
{{hidden|Diagnosis|<center>[[uterine leiomyoma|LEIOMYOMA]] WITH TRANEXAMIC ACID ASSOCIATED MICROINFARCTION</center><br> | {{hidden|Diagnosis|<center>[[uterine leiomyoma|LEIOMYOMA]] WITH TRANEXAMIC ACID ASSOCIATED MICROINFARCTION</center><br> | ||
This smooth muscle tumor depicts no atypia. When in this situation it is prudent to request detailed [[clinical history]]. Clinicians often do not inform of all agents given to patients to control uterine bleeding. | This smooth muscle tumor depicts no atypia. When in this situation it is prudent to request detailed [[clinical history]]. Clinicians often do not inform of all agents given to patients to control uterine bleeding.<ref name=pmid17667546>{{Cite journal | last1 = Ip | first1 = PP. | last2 = Lam | first2 = KW. | last3 = Cheung | first3 = CL. | last4 = Yeung | first4 = MC. | last5 = Pun | first5 = TC. | last6 = Chan | first6 = QK. | last7 = Cheung | first7 = AN. | title = Tranexamic acid-associated necrosis and intralesional thrombosis of uterine leiomyomas: a clinicopathologic study of 147 cases emphasizing the importance of drug-induced necrosis and early infarcts in leiomyomas. | journal = Am J Surg Pathol | volume = 31 | issue = 8 | pages = 1215-24 | month = Aug | year = 2007 | doi = 10.1097/PAS.0b013e318032125e | PMID = 17667546 }}</ref> | ||
===References=== | ===References=== | ||
{{Reflist|1}} | {{Reflist|1}} | ||
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[[Category:Cases]] | [[Category:Cases]] | ||
[[Category:Cases in gynecologic pathology]] | [[Category:Cases in gynecologic pathology]] | ||
- | [[Category:Cases in gynecologic pathology - fellow and expert]] | ||
[[Category:Cases difficulty 7]] <!-- difficulty 1-7 -- should roughly correspond to the PGY level --> | [[Category:Cases difficulty 7]] <!-- difficulty 1-7 -- should roughly correspond to the PGY level --> | ||
Latest revision as of 03:17, 27 September 2015
Provided clinical history
45 year old woman, with intractable uterine bleeding unresponsive to hormone therapy. Mass lesion in the myometrium
Site
Uterus- myometrium
Primary image
High magnification
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Differential diagnosis
Differential diagnosis
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Additional tests
More history
More history
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Ask a colleague
Ask a colleague
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Stains
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IHC
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Molecular testing
Chromosomal translocations
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Other molecular tests
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Diagnosis
Diagnosis
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This smooth muscle tumor depicts no atypia. When in this situation it is prudent to request detailed clinical history. Clinicians often do not inform of all agents given to patients to control uterine bleeding.[1] References
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