Smooth muscle tumour of uncertain malignant potential
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Smooth muscle tumour of uncertain malignant potential, abbreviated STUMP, is smooth muscle lesion in which the behaviour (benign vs. malignant) cannot be ascertained with certainty.
This entity should not be confused with the prostatic stromal tumour that is occasionally abbreviated STUMP.
General
- Like ASAP and ASCUS - a waffle category... when one isn't sure it is a leiomyoma vs. leiomyosarcoma.
- Clinical behaviour in uterus: usually benign.[1]
- Can be subclassified into four groups - as per Stanford.
Management:
- Long-term follow-up.[1]
Microscopic
Features associated with recurrence:[1]
- Nuclear atypia.
DDx:
IHC
Features associated with recurrence:[1]
- p16 +ve.
- p53 +ve.
See also
References
- ↑ Jump up to: 1.0 1.1 1.2 1.3 Ip PP, Cheung AN, Clement PB (July 2009). "Uterine smooth muscle tumors of uncertain malignant potential (STUMP): a clinicopathologic analysis of 16 cases". Am. J. Surg. Pathol. 33 (7): 992–1005. doi:10.1097/PAS.0b013e3181a02d1c. PMID 19417585.