Smooth muscle tumour of uncertain malignant potential
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Smooth muscle tumour of uncertain malignant potential, abbreviated STUMP, is smooth muscle lesion in which the behaviour (benign vs. malignant) cannot be ascertained with certainty.
This entity should not be confused with the prostatic stromal tumour that is occasionally abbreviated STUMP.
General
- Like ASAP and ASCUS - a waffle category... when one isn't sure it is a leiomyoma vs. leiomyosarcoma.
- Clinical behaviour in uterus: usually benign.[1]
- Can be subclassified into four groups - as per Stanford.
Management:
- Long-term follow-up.[1]
Microscopic
Features associated with recurrence:[1]
- Nuclear atypia.
DDx:
IHC
Features associated with recurrence:[1]
- p16 +ve.
- p53 +ve.