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Difference between revisions of "Dermatopathology"
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→Non-malignant non-cystic: subdivide more -- re-arr
m (→Common entities in tables: +pilomatricoma) |
(→Non-malignant non-cystic: subdivide more -- re-arr) |
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| Line 94: | Line 94: | ||
=Common entities in tables= | =Common entities in tables= | ||
==Non-malignant non-cystic== | ==Non-malignant non-cystic - very common== | ||
{| class="wikitable sortable" style="margin-left:auto;margin-right:auto" | {| class="wikitable sortable" style="margin-left:auto;margin-right:auto" | ||
! Entity | ! Entity | ||
| Line 140: | Line 140: | ||
| variants: angiolipoma (blood vessels), myolipoma (muscle) | | variants: angiolipoma (blood vessels), myolipoma (muscle) | ||
| [http://circ.ahajournals.org/content/113/21/e778/F5.expansion.html (ahajournals.org)] | | [http://circ.ahajournals.org/content/113/21/e778/F5.expansion.html (ahajournals.org)] | ||
|- | |- | ||
| [[Keloid]] | | [[Keloid]] | ||
| Line 156: | Line 147: | ||
| none | | none | ||
| [[dermatofibroma]] (???) | | [[dermatofibroma]] (???) | ||
| | | hypertrophic scar | ||
| [http://missinglink.ucsf.edu/lm/DermatologyGlossary/keloids.html (ucsf.edu)]. | | [http://missinglink.ucsf.edu/lm/DermatologyGlossary/keloids.html (ucsf.edu)]. | ||
|- <!-- | |||
| Entity | |||
| Key histologic features | |||
| Other features | |||
| Clinical | |||
| Stains/IHC | |||
| DDx | |||
| Other | |||
| Image --> | |||
|} | |||
==Non-malignant non-cystic - common== | |||
{| class="wikitable sortable" style="margin-left:auto;margin-right:auto" | |||
! Entity | |||
! Key histologic feature | |||
! Other features | |||
! Clinical | |||
! Stains/IHC | |||
! DDx | |||
! Other | |||
! Image | |||
|- | |- | ||
| [[Neurofibroma]] | | [[Neurofibroma]] | ||
| Line 185: | Line 198: | ||
| favourite exam case | | favourite exam case | ||
| [http://commons.wikimedia.org/wiki/File:Molluscum_contagiosum_high_mag.jpg (WC)] | | [http://commons.wikimedia.org/wiki/File:Molluscum_contagiosum_high_mag.jpg (WC)] | ||
|- | |- | ||
| [[Verruca vulgaris]] | | [[Verruca vulgaris]] | ||
| Line 222: | Line 217: | ||
| [http://commons.wikimedia.org/wiki/File:Anal_condyloma_%282%29.jpg (WC)] | | [http://commons.wikimedia.org/wiki/File:Anal_condyloma_%282%29.jpg (WC)] | ||
|- | |- | ||
| [[ | | [[Granuloma annulare]] | ||
| | | dermal palisading [[granuloma]] around necrotic collagen | ||
| | | mucin in centre of lesion, (peripheral) chronic inflammatory cells | ||
| | | benign, self-limited | ||
| | | none (CD68?) | ||
| [[necrobiosis lipoidica]], [[rheumatoid nodule]] | |||
| Other ? | |||
| [http://www.dermaamin.com/site/histopathology-of-the-skin/61-i/1813-interstitial-granuloma-annulare-.html (dermaamin.com)] | |||
|- | |||
| [[Angiofibroma]] | |||
| fibrotic dermis, dilated capillaries | |||
| enlarged (stellate fibroblasts) | |||
| dome-shaped - face, boys & nosebleeds ([[nasopharyngeal angiofibroma]]) | |||
| Stains/IHC | |||
| DDx | | DDx | ||
| | | may be associated with [[tuberous sclerosis]] | ||
| [http:// | | [http://www.drdittmar.lu/images/sce/angiofibroma-s.jpg Angiofibroma (drdittmar.lu)] | ||
|- | |} | ||
==Non-malignant non-cystic - children== | |||
{| class="wikitable sortable" style="margin-left:auto;margin-right:auto" | |||
! Entity | |||
! Key histologic feature | |||
! Other features | |||
! Clinical | |||
! Stains/IHC | |||
! DDx | |||
! Other | |||
! Image | |||
|- | |||
| [[Pilomatricoma]] | | [[Pilomatricoma]] | ||
| anucleate squamous cells (ghost cells), giant cells | | anucleate squamous cells (ghost cells), giant cells | ||
| Line 239: | Line 256: | ||
| mutations of CTNNB1 gene | | mutations of CTNNB1 gene | ||
| [http://commons.wikimedia.org/wiki/File:Pilomatrixoma_-_intermed_mag.jpg (WC)] | | [http://commons.wikimedia.org/wiki/File:Pilomatrixoma_-_intermed_mag.jpg (WC)] | ||
| | |- | ||
| | | [[Juvenile xanthogranuloma]] (JXG) | ||
| | | Touton giant cells - multi-nucleated cells where nuclei are distributed around the cell periphery forming a ring | ||
| | | abundant cytoplasm | ||
| | | children | ||
| | | CD68+, CD1a-, CD207- | ||
| | | [[Langerhans cell histiocytosis]] | ||
| Other | | Other ? | ||
| | | [http://commons.wikimedia.org/wiki/File:Juvenile_xanthogranuloma_-_intermed_mag.jpg (WC)] | ||
|} | |} | ||