Steatocystoma

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Steatocystoma
Diagnosis in short

Steatocystoma. H&E stain.

LM cyst lined by squamous epithelium with a corrugated eosinophilic lining, no granular cell layer
Site skin - see dermal cysts

Syndromes steatocystoma multiplex

Prevalence rare
Prognosis benign

Steatocystoma is a rare benign dermal cyst.

General

  • Benign.
  • Rare.[1]
  • Typically adults.
  • Usually on the trunk.
  • May be genetic; known as steatocystoma multiplex.[2]
    • Classically autosomal dominant.[3]

Microscopic

Features:[4]

  • Cyst lined by squamous epithelium with:
    1. Corrugated eosinophilic lining - key feature.
      • Similar appearance to compact keratin (hyperkeratosis).
      • Described as a hyaline cuticle.[5]
    2. No granular cell layer.

Images

www:

See also

References

  1. Gordon Spratt, EA.; Kaplan, J.; Patel, RR.; Kamino, H.; Ramachandran, SM. (Dec 2013). "Steatocystoma.". Dermatol Online J 19 (12): 20721. PMID 24365012.
  2. Online 'Mendelian Inheritance in Man' (OMIM) 184500
  3. URL: http://path.upmc.edu/cases/case674/dx.html. Accessed on: 29 January 2012.
  4. Busam, Klaus J. (2009). Dermatopathology: A Volume in the Foundations in Diagnostic Pathology Series (1st ed.). Saunders. pp. 312. ISBN 978-0443066542.
  5. URL: http://path.upmc.edu/cases/case674/dx.html. Accessed on: 29 January 2012.
  6. URL: http://path.upmc.edu/cases/case674.html. Accessed on: 29 January 2012.