Difference between revisions of "Case 59"
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Low magnification. H&E stain.
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===Provided clinical history=== | ===Provided clinical history=== | ||
73 year old woman, sigmoidectomy for foreign body perforation | |||
===Site=== | ===Site=== | ||
lymph node from sigmoidectomy specimen | |||
===Primary image=== | ===Primary image=== | ||
[[Image: | [[Image: Chronic lymphocytic leukemia - low mag.jpg |500px|link=|center|]] | ||
<center>Low magnification. [[H&E stain]].</center> | <center>Low magnification. [[H&E stain]].</center> | ||
{{hidden|Intermediate magnification|[[Image: | {{hidden|Intermediate magnification|[[Image: Chronic lymphocytic leukemia - intermed mag.jpg |500px|link=|center|]] | ||
<center>Intermediate magnification. [[H&E stain]].</center>}} | <center>Intermediate magnification. [[H&E stain]].</center>}} | ||
{{hidden|High magnification|[[Image: | {{hidden|High magnification|[[Image: Chronic lymphocytic leukemia - high mag.jpg |500px|link=|center|]] | ||
<center>High magnification. [[H&E stain]].</center>}} | <center>High magnification. [[H&E stain]].</center>}} | ||
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===Differential diagnosis=== | ===Differential diagnosis=== | ||
{{hidden|Differential diagnosis|<center>THE DDx GOES HERE</center>}} | {{hidden|Differential diagnosis|<center>THE DDx GOES HERE</center>}} | ||
--> | |||
===Additional tests=== | ===Additional tests=== | ||
====More history==== | ====More history==== | ||
{{hidden|More history|<center> | {{hidden|More history|<center>Chicken bone lead to sigmoid perforation. Large lymph node found during operation - sent to pathology. Mild leukocytosis.</center>}} | ||
====Ask a colleague==== | ====Ask a colleague==== | ||
{{hidden|Ask a colleague|<center> | {{hidden|Ask a colleague|<center>Could be neoplastic... did you do stains?</center>}} | ||
====Stains==== | ====Stains==== | ||
| Line 82: | Line 82: | ||
| b72_3= | | b72_3= | ||
| bcatenin= | | bcatenin= | ||
| bcl2= | | bcl2= '''POSITIVE''' | ||
| bcl6= | | bcl6= | ||
| bclxl= | | bclxl= | ||
| Line 95: | Line 95: | ||
| cd15= | | cd15= | ||
| cd1a= | | cd1a= | ||
| cd20= | | cd20= '''POSITIVE''' | ||
| cd21= | | cd21= | ||
| cd23= | | cd23= '''POSITIVE''' | ||
| cd3= | | cd3= mostly '''NEGATIVE''' | ||
| cd30= | | cd30= | ||
| cd31= | | cd31= | ||
| Line 105: | Line 105: | ||
| cd4= | | cd4= | ||
| cd43= | | cd43= | ||
| cd45= '''POSITIVE''' | |||
| cd45= | | cd45= | ||
| cd5= '''POSITIVE''' | |||
| cd5= | |||
| cd56= | | cd56= | ||
| cd57= | | cd57= | ||
| Line 127: | Line 127: | ||
| cmv= | | cmv= | ||
| cmyc= | | cmyc= | ||
| cyclin_d1= | | cyclin_d1= '''NEGATIVE''' | ||
| d2_40= | | d2_40= | ||
| desmin= | | desmin= | ||
| Line 242: | Line 242: | ||
===Diagnosis=== | ===Diagnosis=== | ||
{{hidden|Diagnosis|<center> | {{hidden|Diagnosis|<center>[[Small lymphocytic lymphoma]]</center>}} | ||
<br> | <br> | ||
===Other cases=== | ===Other cases=== | ||
Revision as of 01:20, 26 May 2014
Provided clinical history
73 year old woman, sigmoidectomy for foreign body perforation
Site
lymph node from sigmoidectomy specimen
Primary image
Intermediate magnification
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High magnification
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Additional tests
More history
More history
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Ask a colleague
Ask a colleague
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Stains
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IHC
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Chromosomal translocations
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Diagnosis
Diagnosis
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