Difference between revisions of "Urinary bladder"

From Libre Pathology
Jump to navigation Jump to search
 
(5 intermediate revisions by the same user not shown)
Line 1: Line 1:
The '''urinary bladder''' stores urine until one has to go pee. It gets the urine from the [[ureter]]s and exspells it via the [[urethra]].
The '''urinary bladder''' stores urine between urination, i.e. trips to the washroom to go pee. It gets the urine from the [[ureter]]s and exspells it via the [[urethra]].


It is commonly afflicted by [[cancer]]. A well-know mimicker of cancer is ''[[malakoplakia]]''.<ref name=pmid17102055>{{cite journal |author=Wong-You-Cheong JJ, Woodward PJ, Manning MA, Davis CJ |title=From the archives of the AFIP: Inflammatory and nonneoplastic bladder masses: radiologic-pathologic correlation |journal=Radiographics |volume=26 |issue=6 |pages=1847–68 |year=2006 |pmid=17102055 |doi=10.1148/rg.266065126 |url=}}</ref>
It is commonly afflicted by [[cancer]]. A well-know mimicker of cancer is ''[[malakoplakia]]''.<ref name=pmid17102055>{{cite journal |author=Wong-You-Cheong JJ, Woodward PJ, Manning MA, Davis CJ |title=From the archives of the AFIP: Inflammatory and nonneoplastic bladder masses: radiologic-pathologic correlation |journal=Radiographics |volume=26 |issue=6 |pages=1847–68 |year=2006 |pmid=17102055 |doi=10.1148/rg.266065126 |url=}}</ref>
Line 45: Line 45:
==Urachal carcinoma==
==Urachal carcinoma==
{{Main|Urachal carcinoma}}
{{Main|Urachal carcinoma}}
=Other=
==Urinary bladder infarct==
{{Main|Infarction}}
===General===
*Case report rare - as the organ has many colaterals.<ref name=pmid3394185>{{Cite journal  | last1 = Nino-Murcia | first1 = M. | last2 = Friedland | first2 = GW. | title = Bladder infarct. | journal = Urol Radiol | volume = 9 | issue = 4 | pages = 234-6 | month =  | year = 1988 | doi =  | PMID = 3394185 }}</ref>
*May be seen in association with [[pseudocarcinomatous urothelial hyperplasia]].<ref name=pmid23228381>{{Cite journal  | last1 = Kryvenko | first1 = ON. | last2 = Epstein | first2 = JI. | title = Pseudocarcinomatous urothelial hyperplasia of the bladder: clinical findings and followup of 70 patients. | journal = J Urol | volume = 189 | issue = 6 | pages = 2083-6 | month = Jun | year = 2013 | doi = 10.1016/j.juro.2012.12.005 | PMID = 23228381 }}</ref>
===Microscopic===
Features:<ref name=pmid3394185/>
*[[Necrosis]] without liquefaction.
**Outlines of cells visible.
**No nuclei present.
Note:
*Liquefaction implies an infectious etiology.<ref name=pmid3394185/>


==Rhabdomyosarcoma of the urinary bladder==
==Rhabdomyosarcoma of the urinary bladder==
Line 76: Line 60:
**Used if no carcinomatous component is identified with extensive sampling.  
**Used if no carcinomatous component is identified with extensive sampling.  
*[[Small cell carcinoma of the urinary bladder]].
*[[Small cell carcinoma of the urinary bladder]].
**Should be positive for keratins and chromogranin A.
**Should be positive for [[keratins]] and chromogranin A.


===IHC===
===IHC===
Line 83: Line 67:
*Myogenin +ve.
*Myogenin +ve.
*Keratins -ve.
*Keratins -ve.
==Metastasis to the urinary bladder==
{{Main|Urinary bladder metastasis}}
=Other=
==Urinary bladder infarct==
{{Main|Infarction}}
===General===
*Case report rare - as the organ has many colaterals.<ref name=pmid3394185>{{Cite journal  | last1 = Nino-Murcia | first1 = M. | last2 = Friedland | first2 = GW. | title = Bladder infarct. | journal = Urol Radiol | volume = 9 | issue = 4 | pages = 234-6 | month =  | year = 1988 | doi =  | PMID = 3394185 }}</ref>
*May be seen in association with [[pseudocarcinomatous urothelial hyperplasia]].<ref name=pmid23228381>{{Cite journal  | last1 = Kryvenko | first1 = ON. | last2 = Epstein | first2 = JI. | title = Pseudocarcinomatous urothelial hyperplasia of the bladder: clinical findings and followup of 70 patients. | journal = J Urol | volume = 189 | issue = 6 | pages = 2083-6 | month = Jun | year = 2013 | doi = 10.1016/j.juro.2012.12.005 | PMID = 23228381 }}</ref>
===Microscopic===
Features:<ref name=pmid3394185/>
*[[Necrosis]] without liquefaction.
**Outlines of cells visible.
**No nuclei present.
Note:
*Liquefaction implies an infectious etiology.<ref name=pmid3394185/>


==Urinary bladder amyloidosis==
==Urinary bladder amyloidosis==
Line 89: Line 92:
==Tubular adenoma of the urinary bladder==
==Tubular adenoma of the urinary bladder==
{{Main|Tubular adenoma of the urinary tract}}
{{Main|Tubular adenoma of the urinary tract}}
==Keratinising squamous metaplasia of the urinary bladder==
{{Main|Keratinising squamous metaplasia of the urinary bladder}}
==Leiomyoma of the urinary bladder==
{{Main|Leiomyoma of the urinary bladder}}


==Cystitis==
==Cystitis==

Latest revision as of 03:23, 17 January 2017

The urinary bladder stores urine between urination, i.e. trips to the washroom to go pee. It gets the urine from the ureters and exspells it via the urethra.

It is commonly afflicted by cancer. A well-know mimicker of cancer is malakoplakia.[1]

Normal

Microscopic

  • Muscularis mucosae - thin, discontinuous.
  • Fat - many be in lamina propria.

Note:

  • On TURBT - don't ever call pT3.

Grossing

AKA cut-up.

Urinary bladder cancer

The most common type of cancer to affect the bladder is urothelial carcinoma. This is covered in the urothelium article.

Risk factors for bladder cancer SEX LIC:

  • Schistomsoma haematobium - esp. squamous cell carcinoma.[2]
  • EXtrophy of the bladder.
  • Lithiasis.
  • Indwelling catheter or chronic Inflammation.[2]
  • Cyclophosphamide.

DDx:

Squamous cell carcinoma of the urinary bladder

  • Rare type of bladder cancer.
  • Urothelial carcinoma with squamous differentiation is much more common.

Urachal carcinoma

Rhabdomyosarcoma of the urinary bladder

General

  • Considered extremely rare in adults.[3]

Microscopic

See rhabdomyosarcoma.

DDx:

  • Rhabdomyosarcomatous sarcomatoid carcinoma - more common than RMS in adults.
    • Requires the identification of a carcinoma component.
  • Rhabdomyomatous tumour.[3]
    • Used if no carcinomatous component is identified with extensive sampling.
  • Small cell carcinoma of the urinary bladder.
    • Should be positive for keratins and chromogranin A.

IHC

Features:[3]

  • Desmin +ve.
  • Myogenin +ve.
  • Keratins -ve.

Metastasis to the urinary bladder

Other

Urinary bladder infarct

General

Microscopic

Features:[4]

  • Necrosis without liquefaction.
    • Outlines of cells visible.
    • No nuclei present.

Note:

  • Liquefaction implies an infectious etiology.[4]

Urinary bladder amyloidosis

Tubular adenoma of the urinary bladder

Keratinising squamous metaplasia of the urinary bladder

Leiomyoma of the urinary bladder

Cystitis

See urothelium.

See also

References

  1. Wong-You-Cheong JJ, Woodward PJ, Manning MA, Davis CJ (2006). "From the archives of the AFIP: Inflammatory and nonneoplastic bladder masses: radiologic-pathologic correlation". Radiographics 26 (6): 1847–68. doi:10.1148/rg.266065126. PMID 17102055.
  2. 2.0 2.1 Michaud, DS.. "Chronic inflammation and bladder cancer.". Urol Oncol 25 (3): 260-8. doi:10.1016/j.urolonc.2006.10.002. PMID 17483025.
  3. 3.0 3.1 3.2 3.3 Bing, Z.; Zhang, PJ. (2011). "Adult urinary bladder tumors with rhabdomyosarcomatous differentiation: clinical, pathological and immunohistochemical studies.". Diagn Pathol 6: 66. doi:10.1186/1746-1596-6-66. PMID 21762516.
  4. 4.0 4.1 4.2 Nino-Murcia, M.; Friedland, GW. (1988). "Bladder infarct.". Urol Radiol 9 (4): 234-6. PMID 3394185.
  5. Kryvenko, ON.; Epstein, JI. (Jun 2013). "Pseudocarcinomatous urothelial hyperplasia of the bladder: clinical findings and followup of 70 patients.". J Urol 189 (6): 2083-6. doi:10.1016/j.juro.2012.12.005. PMID 23228381.