Difference between revisions of "Case 107"
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Low magnification. H&E stain.
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===Diagnosis=== | ===Diagnosis=== | ||
{{hidden|Diagnosis|<center>CLEAR CELL CARCINOMA OF THE OVARY. This is the most commonly missed pattern of clear cells carcinoma in the ovary | {{hidden|Diagnosis|<center>CLEAR CELL CARCINOMA OF THE OVARY. This is the most commonly missed pattern of clear cells carcinoma in the ovary. Another pattern that is commonly missed is the papillary pattern which resembles a borderline serous tumor. Most often the luminal contents are watery, but can be thick and tenacious. The tumor is difficult to recognize because the atypia is not pronounced. Closer examination will reveal hobnailed cells (image 2). Smaller cysts often reveal the diagnostic clear cells. Tumor cells are characteristically WT1, ER, PR negative which distinguishes it from a serous tumor. However, this immunoprofile is also true of mucinous tumors of the ovary, although that is uncommonly in the differential. Tumor cells are positive for Napsin, HNF1beta and Arid IA, which distinguishes it from its mimics. </center>}} | ||
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===Other cases=== | ===Other cases=== | ||
{{Cases navigation}} | {{Cases navigation}} | ||
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[[Category:Cases]] | [[Category:Cases]] | ||
[[Category:Cases in | [[Category:Cases in gynecologic pathology]] | ||
- | [[Category:Cases in gynecologic pathology - senior]] | ||
[[Category:Cases difficulty 4]] <!-- difficulty 1-7 -- should roughly correspond to the PGY level --> | [[Category:Cases difficulty 4]] <!-- difficulty 1-7 -- should roughly correspond to the PGY level --> | ||
Latest revision as of 04:27, 24 September 2015
Provided clinical history
53 year old woman with a 11 cm cystic mass with focal small solid area on ultrasound, thought to be a cystadenoma or cystadenofibroma preoperatively
Site
Ovary- epithelial
Primary image
Intermediate magnification
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High magnification
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Differential diagnosis
Differential diagnosis
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Additional tests
More history
More history
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Ask a colleague
Ask a colleague
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Stains
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IHC
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Molecular testing
Chromosomal translocations
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Other molecular tests
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Diagnosis
Diagnosis
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