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Difference between revisions of "Case 6"
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===Additional tests=== | ===Additional tests=== | ||
====More history==== | ====More history==== | ||
{{hidden|More history|<center>Discovered testicular mass on self-exam. Serum | {{hidden|More history|<center>Discovered testicular mass on self-exam. Serum hCG elevated.</center>}} | ||
====Ask a friend==== | ====Ask a friend==== | ||
{{hidden|Ask a friend|<center>Can't help think about [[chorionic villi]].</center>}} | {{hidden|Ask a friend|<center>Can't help think about [[chorionic villi]]. Did you try a hCG IHC?</center>}} | ||
====Stains==== | ====Stains==== | ||
| Line 63: | Line 63: | ||
| warthinstarry= | | warthinstarry= | ||
}} | }} | ||
====IHC==== | ====IHC==== | ||
{{Case IHC | {{Case IHC | ||
| Line 106: | Line 105: | ||
| cea= | | cea= | ||
| chromo= | | chromo= | ||
| ck19= | | ck19= '''POSITIVE''' | ||
| ck20= | | ck20= | ||
| ck34be12= | | ck34be12= | ||
| Line 122: | Line 121: | ||
| fxiiia= | | fxiiia= | ||
| gastrin= | | gastrin= | ||
| gata3= '''POSITIVE''' nuclear staining | |||
| gcdfp= | | gcdfp= | ||
| gh= | | gh= | ||
| | | glucagon= | ||
| glypican3= '''POSITIVE''' | |||
| hbme1= | | hbme1= | ||
| hbvc= | | hbvc= | ||
| Line 176: | Line 177: | ||
| vip= | | vip= | ||
| vzv= | | vzv= | ||
}} | |||
====Chromosomal translocations==== | |||
{{Case Translocations | |||
| blank=Dr Torres would ask why! | |||
| t1_13= | |||
| t11_14= | |||
| t11_22dsrct= | |||
| t11_22ews= | |||
| t12_15= | |||
| t12_16afh= | |||
| t12_16liposar= | |||
| t12_22= | |||
| t14_18= | |||
| t15_17= | |||
| t16_21= | |||
| t17_22= | |||
| t2_13= | |||
| t21_22= | |||
| t8_14= | |||
| t9_22= | |||
| t9_22= | |||
| tx_17= | |||
| tx_18= | |||
}} | }} | ||
===Diagnosis=== | ===Diagnosis=== | ||
{{hidden|Diagnosis|<center>[[Choriocarcinoma]].</ | {{hidden|Diagnosis|<center>[[Choriocarcinoma]]</center> | ||
<br> | |||
Comment:<br> | |||
Histology is important for this diagnosis. [[CK19]] is positive in [[yolk sac tumour]] (YST) and [[choriocarcinoma]].<ref>{{Cite journal | last1 = Bremmer | first1 = F. | last2 = Ströbel | first2 = P. | last3 = Hubertus | first3 = H. | last4 = Strecker | first4 = J. | last5 = Gaisa | first5 = N. | last6 = Strauß | first6 = A. | last7 = Schweyer | first7 = S. | last8 = Radzun | first8 = H-J. | last9 = Behnes | first9 = C-L | title = CK19 is a sensitive marker for yolk sac tumours of the testis. | journal = Diagnostic Pathology | volume = 10 | issue = 7 | pages = | month = | year = 2015 | doi = 10.1186/s13000-015-0243-y | PMID = | url = www.diagnosticpathology.org/content/10/1/7Cached }}</ref> Glypican 3 can be positive in choriocarcinoma; it is usually positive in YST. | |||
===Reference=== | |||
{{Reflist|1}} | |||
}} | |||
<br> | |||
===Other cases=== | |||
{{Cases navigation|state=collapsed}} | |||
__NOTOC__ | __NOTOC__ | ||
[[Category:Cases]] | [[Category:Cases]] | ||
[[Category:Cases in genitourinary pathology]] | |||
[[Category:Cases difficulty 3]] | |||
[[Category:Cases in genitourinary pathology - junior]] | |||