Difference between revisions of "Placenta"

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453 bytes added ,  17:20, 8 February 2011
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=Maternal disease=
=Maternal disease=
==Hypertensive changes==
==Hypertensive changes==
Features:<ref name=pmid6754249>{{cite journal |author=Soma H, Yoshida K, Mukaida T, Tabuchi Y |title=Morphologic changes in the hypertensive placenta |journal=Contrib Gynecol Obstet |volume=9 |issue= |pages=58–75 |year=1982 |pmid=6754249 |doi= |url=}}</ref>
===General===
*Enlarged endothelial cells - fetal capillaries.
Associated pathologic changes:<ref name=pmid6754249>{{cite journal |author=Soma H, Yoshida K, Mukaida T, Tabuchi Y |title=Morphologic changes in the hypertensive placenta |journal=Contrib Gynecol Obstet |volume=9 |issue= |pages=58–75 |year=1982 |pmid=6754249 |doi= |url=}}</ref>
*Atherosis of the spiral arteries - placental bed (maternal).
 
Associated changes:<ref name=pmid6754249/>
*Placental infarcts.  
*Placental infarcts.  
*Increased syncytial knots.
*Increased syncytial knots.
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*Thickening of the trophoblastic basement membrane.
*Thickening of the trophoblastic basement membrane.


===Hypertrophic decidual vasculopathy===
===Microscopic===
Features:<ref name=pmid6754249>{{cite journal |author=Soma H, Yoshida K, Mukaida T, Tabuchi Y |title=Morphologic changes in the hypertensive placenta |journal=Contrib Gynecol Obstet |volume=9 |issue= |pages=58–75 |year=1982 |pmid=6754249 |doi= |url=}}</ref>
*Enlarged endothelial cells - fetal capillaries.
*Atherosis of the spiral arteries - placental bed (maternal).
 
Notes:
*One should look for the changes in the membrane roll, not the maternal surface.<ref>CS. 7 February 2011.</ref>
 
==Hypertrophic decidual vasculopathy==
===General===
*A change seen in hypertension.
 
===Microscopic===
Features:<ref name=pmid18641412>{{Cite journal  | last1 = Roberts | first1 = DJ. | last2 = Post | first2 = MD. | title = The placenta in pre-eclampsia and intrauterine growth restriction. | journal = J Clin Pathol | volume = 61 | issue = 12 | pages = 1254-60 | month = Dec | year = 2008 | doi = 10.1136/jcp.2008.055236 | PMID = 18641412 }}</ref>
Features:<ref name=pmid18641412>{{Cite journal  | last1 = Roberts | first1 = DJ. | last2 = Post | first2 = MD. | title = The placenta in pre-eclampsia and intrauterine growth restriction. | journal = J Clin Pathol | volume = 61 | issue = 12 | pages = 1254-60 | month = Dec | year = 2008 | doi = 10.1136/jcp.2008.055236 | PMID = 18641412 }}</ref>
*Mild or moderate:
*Mild or moderate:
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