Red blood cell

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Abundant red blood cells in the vascular channels of a hemangioma. H&E stain.
Nucleated red blood cells in an endometrial polyp. H&E stain.

The red blood cell, abbreviated RBC, is the carrier of oxygen to tissue. It is seen daily by pathologists.

It is approximately 8 micrometers in diameter.[1]

Precursors

Reticulocyte

The direct precursor to the RBC is the reticulocyte.

Image:

Normoblast

Normoblasts are the nucleated precursors of RBCs.

Images:

Conditions with RBCs

Sickle cell disease

Anemia

Hemophagocytic syndrome

  • Macrophages eat whole RBCs.

Myospherulosis

General

Etiology:

Microscopic

Features:

  • Phagocytosed RBCs.
    • Round aggregates of red blood cells ~10-20 RBCs in diameter (80-160 micrometers).

See also

References

  1. URL: http://www.wisegeek.com/how-large-is-a-micrometer.htm. Accessed on: 17 January 2011.
  2. 2.0 2.1 2.2 Godbersen, GS.; Kleeberg, J.; Lüttges, J.; Werner, JA. (Sep 1995). "[Spherulocytosis (myospherulosis) of the paranasal sinuses].". HNO 43 (9): 552-5. PMID 7591868.
  3. Fisher, SC.; Horning, GM.; Hellstein, JW. (Dec 2001). "Myospherulosis complicating cortical block grafting: a case report.". J Periodontol 72 (12): 1755-9. doi:10.1902/jop.2001.72.12.1755. PMID 11811513.
  4. Sarkar, S.; Gangane, N.; Sharma, S. (Oct 1998). "Myospherulosis of maxillary sinus--a case report with review of literature.". Indian J Pathol Microbiol 41 (4): 491-3. PMID 9866916.
  5. Chau, KY.; Pretorius, JM.; Stewart, AW. (Oct 2000). "Myospherulosis in renal cell carcinoma.". Arch Pathol Lab Med 124 (10): 1476-9. doi:10.1043/0003-9985(2000)1241476:MIRCC2.0.CO;2. PMID 11035579.