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Difference between revisions of "Ovarian tumours"
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→Microscopic: expand
(→Peritoneal implants: expand) |
(→Microscopic: expand) |
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===Microscopic=== | ===Microscopic=== | ||
Features (non-invasive implants): | ====Non-invasive implant==== | ||
* | Features (non-invasive implant epithelial-type):<ref name=pmid3179935>{{Cite journal | last1 = Bell | first1 = DA. | last2 = Weinstock | first2 = MA. | last3 = Scully | first3 = RE. | title = Peritoneal implants of ovarian serous borderline tumors. Histologic features and prognosis. | journal = Cancer | volume = 62 | issue = 10 | pages = 2212-22 | month = Nov | year = 1988 | doi = | PMID = 3179935 }}</ref> | ||
*Papillary proliferation on surface. | |||
*+/-Smooth contoured invagination into: | |||
**Submesothelium. | |||
**Omental fat lobules. | |||
*No "stromal response": | |||
**Fibrosis. | |||
*+/-[[Psammoma bodies]]. | |||
Features (non-invasive implant desmoplastic-type):<ref name=pmid3179935>{{Cite journal | last1 = Bell | first1 = DA. | last2 = Weinstock | first2 = MA. | last3 = Scully | first3 = RE. | title = Peritoneal implants of ovarian serous borderline tumors. Histologic features and prognosis. | journal = Cancer | volume = 62 | issue = 10 | pages = 2212-22 | month = Nov | year = 1988 | doi = | PMID = 3179935 }}</ref> | |||
*Stromal reaction at restricted to the: | |||
**Serosal surface. | |||
**Fibrous septae. | |||
*+/-[[Psammoma bodies]]. | |||
Note: | |||
*No "destructive invasion". | |||
**Irregular infiltration. | |||
====Invasive implant==== | |||
Features (invasive implant):<ref name=pmid3179935/> | |||
*Irregular infiltration of tumour into the submesothelial tissue - '''key feature''' - characterized by: | |||
**+/-Solid nests. | |||
**+/-Small glands +/- irregular "bridging" connections between glands - '''common'''. | |||
*Nuclear atypia - '''common'''. | |||
*+/-[[Psammoma bodies]]. | |||
===Stains=== | ===Stains=== | ||