Psammoma bodies

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Psammoma bodies in serous carcinoma. H&E stain.
Psammoma bodies in meningioma. H&E stain.

Psammoma bodies appear in benign and malignant conditions. Their presence can help focus the DDx.[1]

They are often associated with a papillary architecture.[citation needed]

Conditions with psammoma bodies

The following is an incomplete list.

Benign

Malignant

Memory device PSaMMoma: Papillary (thyroid, renal), Serous (ovary), Meningioma, Mesothelioma.[11]

Isolated psammoma bodies in smears or aspirates are an unreliable predictor of papillary carcinoma. [12]

See also

References

  1. Parwani, AV.; Chan, TY.; Ali, SZ. (Apr 2004). "Significance of psammoma bodies in serous cavity fluid: a cytopathologic analysis.". Cancer 102 (2): 87-91. doi:10.1002/cncr.20161. PMID 15098252.
  2. Minkowitz, G. (Jun 1996). "Psammoma bodies in endometriosis: clinical, cytological, and physiopathological implications.". Diagn Cytopathol 14 (4): 331-3. doi:10.1002/(SICI)1097-0339(199605)14:4<331::AID-DC11>3.0.CO;2-L. PMID 8725135.
  3. Parwani, AV.; Chan, TY.; Ali, SZ. (Apr 2004). "Significance of psammoma bodies in serous cavity fluid: a cytopathologic analysis.". Cancer 102 (2): 87-91. doi:10.1002/cncr.20161. PMID 15098252.
  4. Boon, ME.; Kirk, RS.; De Graaff Guilloud, JC. (Jul 1981). "Psammoma bodies and some opportunistic infections detected in cervical smears of women fitted with an IUD.". Contracept Deliv Syst 2 (3): 231-6. PMID 12278909.
  5. Fausett MB, Zahn CM, Kendall BS, Barth WH (February 2002). "The significance of psammoma bodies that are found incidentally during endometrial biopsy". Am. J. Obstet. Gynecol. 186 (2): 180–3. PMID 11854631.
  6. KEPES, J. (Apr 1961). "Observations on the formation of psammoma bodies and pseudopsammoma bodies in meningiomas.". J Neuropathol Exp Neurol 20: 255-62. PMID 13752577.
  7. Wolfson, WL.; Rosenthal, DL.; Harney, B.. "Psammoma bodies in pituitary adenoma.". Acta Cytol 23 (1): 90-2. PMID 285558.
  8. Jovanović, I.; Ugrenović, S.; Vasović, L.; Petrović, D.; Cekić, S. (Jun 2010). "Psammoma bodies - friends or foes of the aging choroid plexus.". Med Hypotheses 74 (6): 1017-20. doi:10.1016/j.mehy.2010.01.006. PMID 20116930.
  9. Kim, JA.; Choi, WH.; Kim, CN.; Moon, YS.; Chang, SH.; Lee, HR. (Mar 2011). "Duodenal somatostatinoma: a case report and review.". Korean J Intern Med 26 (1): 103-7. doi:10.3904/kjim.2011.26.1.103. PMID 21437171.
  10. KEPES, J. (Apr 1961). "Observations on the formation of psammoma bodies and pseudopsammoma bodies in meningiomas.". J Neuropathol Exp Neurol 20: 255-62. PMID 13752577.
  11. URL: http://ome.umaryland.edu/AcademicD/practiceExams/path/path_findings.html. Accessed on: 15 January 2012.
  12. Ellison, E.; Lapuerta, P.; Martin, SE. (Jun 1998). "Psammoma bodies in fine-needle aspirates of the thyroid: predictive value for papillary carcinoma.". Cancer 84 (3): 169-75. PMID 9678732.