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Difference between revisions of "Talk:Microsatellite instability in colorectal cancer"
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Talk:Microsatellite instability in colorectal cancer (view source)
Revision as of 15:23, 19 March 2025
, 19 March→MLH1 loss and BRAF V600E
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==MLH1 loss and BRAF V600E== | ==MLH1 loss and BRAF V600E== | ||
"... epigenetic inactivation of MLH1 in tumors that often carry mutations in oncogenic BRAFV600E." https://pubmed.ncbi.nlm.nih.gov/25386108/ | "... epigenetic inactivation of MLH1 in tumors that often carry mutations in oncogenic BRAFV600E." https://pubmed.ncbi.nlm.nih.gov/25386108/ | ||
"If a BRAF V600E mutation is present, loss of MLH1 is likely sporadic in nature and MLH1 hypermethylation testing is not indicated." | |||
==Unusually MMR loss== | ==Unusually MMR loss== | ||