Talk:Microsatellite instability in colorectal cancer

From Libre Pathology

Jump to navigation Jump to search

Heterogenous staining

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463865/

MLH1 loss and BRAF V600E

"... epigenetic inactivation of MLH1 in tumors that often carry mutations in oncogenic BRAFV600E." https://pubmed.ncbi.nlm.nih.gov/25386108/

Unusually MMR loss

https://pmc.ncbi.nlm.nih.gov/articles/PMC8860743/ - isolated MSH6 and isolated PMS2 are the most common of the uncommon loss patterns

Retrieved from "https://librepathology.org/w/index.php?title=Talk:Microsatellite_instability_in_colorectal_cancer&oldid=53354"