Difference between revisions of "Squamous intraepithelial lesion of the uterine cervix"

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===Low-grade squamous intraepithelial lesion===
===Low-grade squamous intraepithelial lesion===
{{Main|Low-grade squamous intraepithelial lesion}}
{{Main|Low-grade squamous intraepithelial lesion}}
====Koilocytes versus benign squamous====
Koilocytes:
*Perinuclear clearing.
*Nuclear changes.
**Size similar (or larger) to those in the basal layer of the epithelium.
**Nuclear enlargement should be evident on low power, i.e. 25x. <ref>V. Dube 2008.</ref>
**Central location - nucleus should be smack in the middle of the cell.
Notes:
# Both perinuclear clearing and nuclear changes are essential.
# Benign cells have a small nucleus that is peripheral.
====Images====
<gallery>
Image: Low-grade squamous intraepithelial lesion -- intermed mag.jpg | LSIL - intermed. mag. (WC)
Image: Low-grade squamous intraepithelial lesion -- p16 - intermed mag.jpg | LSIL - intermed. mag. (WC)
Image: Low-grade squamous intraepithelial lesion -- high mag.jpg | LSIL - high mag. (WC)
Image: Low-grade squamous intraepithelial lesion -- very high mag.jpg | LSIL - very high mag. (WC)
</gallery>
<gallery>
Image:Cervical intraepithelial neoplasia (2) koilocytosis.jpg| CIN I. (WC/KGH)
</gallery>
www:
*[http://www.flickr.com/photos/jian-hua_qiao_md/3987000055/ CIN 1 (flickr.com/Qiao)].
*[http://www.eurocytology.eu/static/eurocytology/eng/cervical/mod6img1a.html CIN 1 (eurocytology.eu)].


===High-grade squamous intraepithelial lesion===
===High-grade squamous intraepithelial lesion===
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