Talk:Squamous intraepithelial lesion of the uterine cervix
From Libre Pathology
UTERINE CERVIX, BIOPSY: - SQUAMOUS INTRAEPITHELIAL LESION, FAVOUR HIGH-GRADE -- SMALL FOCUS, SEE COMMENT. - BENIGN ENDOCERVICAL EPITHELIUM PRESENT. COMMENT: The cytology has intermediate features. A p16 immunostain strongly marks the full thickness of the thin (abnormal) squamous epithelium seen in the plane of section, and a Ki-67 focally shows positive superficial cells. These findings favour the presence of a high-grade squamous intraepithelial lesion (HSIL). A re-biopsy with close follow-up could be considered.
UTERINE CERVIX, 12 O'CLOCK, BIOPSY: - HIGH-GRADE SQUAMOUS INTRAEPITHELIAL LESION (HSIL). - VERY SCANT STRIPPED ENDOCERVICAL EPITHELIUM. - ACUTE AND CHRONIC INFLAMMATION. COMMENT: A p16 immunostain marks the full thickness of the squamous epithelium and is strong. A Ki-67 immunostain marks a mildly increased number of superficial epithelial cells. A immunostain shows basal staining and superficial non-staining in the region of HSIL.