Difference between revisions of "Squamous intraepithelial lesion of the uterine cervix"

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Squamous intraepithelial lesion of the uterine cervix (view source)

Revision as of 20:01, 30 January 2014

1,336 bytes removed ,  20:01, 30 January 2014
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===Cervical biopsy===
===Cervical biopsy===
====LSIL====
<pre>
UTERINE CERVIX, BIOPSY:
- LOW-GRADE SQUAMOUS INTRAEPITHELIAL LESION (LSIL).
- NO ENDOCERVICAL EPITHELIUM IDENTIFIED.
</pre>
<pre>
UTERINE CERVIX, BIOPSY:
- LOW-GRADE SQUAMOUS INTRAEPITHELIAL LESION (LSIL).
- TRANSFORMATION ZONE PRESENT.
</pre>
<pre>
UTERINE CERVIX, BIOPSY:
- LOW-GRADE SQUAMOUS INTRAEPITHELIAL LESION (LSIL).
- CERVICITIS, CHRONIC.
- NO ENDOCERVICAL EPITHELIUM IDENTIFIED.
</pre>
<pre>
UTERINE CERVIX, BIOPSY:
- LOW-GRADE SQUAMOUS INTRAEPITHELIAL LESION (LSIL).
- TRANSFORMATION ZONE PRESENT.
COMMENT:
A p16 stain is patchy and confined mostly to the lower aspect of the squamous epithelium.
</pre>
====CIN 1====
<pre>
UTERINE CERVIX, BIOPSY:
- CERVICAL INTRAEPITHELIAL NEOPLASIA 1 (MILD DYSPLASIA).
- TRANSFORMATION ZONE PRESENT.
</pre>
<pre>
COMMENT:
The Ki-67 positive cells are confined to the lower aspect of the squamous epithelium. 
A p16 stain is negative.
</pre>
====At least CIN 2====
====At least CIN 2====
<pre>
<pre>
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===Micro===
===Micro===
====CIN 1====
The sections show the transformation zone. The squamous epithelium has cells with an increased nuclear size, nuclear hyperchromasia, perinuclear clearing and irregularities in the nuclear membrane. The nucleus-to-cytoplasm ratio is mildly increased. Occasional binucleation is identified. Mitoses are seen in the low third of the epithelium. Nucleoli are not apparent. No columnar dysplasia is identified.
====CIN 2====
====CIN 2====
The sections show the transformation zone.
The sections show the transformation zone.
Michael
48,830

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