Difference between revisions of "Synaptophysin"

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(+neuropathology)
(→‎Tumours: +more added)
 
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* Substantia nigra  
* Substantia nigra  
* Cerebellum  system   
* Cerebellum  system   
* Olfactory  bulb  
* Olfactory  bulb
* Pineal gland
* Adrenal gland
* Langerhans islets


==Tumours==
==Tumours==
* [[Ganglioglioma]]
* [[Ganglioglioma]].
* [[Medulloblastoma]] +/-ve.
* [[Medulloblastoma]] +/-ve.
* [[Pituitary adenoma]]
* [[Pituitary adenoma]].
* [[Neurocytoma]].
* [[Paraganglioma]].
* [[Dysembryoplastic neuroepithelial tumour]].
* [[Atypical carcinoid]].




===Negative staining===
===Negative staining===


==See also==
==See also==

Latest revision as of 12:02, 8 April 2019

Synaptophysin staining in Atypical carcinoid.

Synaptophysin is the principal structural element of the walls of synaptic vesicles and thus a neuroendocrine marker.

Normal tissues

  • Note: resists autolytic degradation (can be used 5 days post mortem).
  • Marker of late onset (neuronal maturation).

Positive staining

  • Cerebral cortex
  • Hippocampus
  • Corpus striatum,
  • Globus pallidus
  • Substantia nigra
  • Cerebellum system
  • Olfactory bulb
  • Pineal gland
  • Adrenal gland
  • Langerhans islets

Tumours


Negative staining

See also

References