Difference between revisions of "Inflammatory pseudopolyp"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = | |||
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| Micro = polypoid shape, inflammatory cells - esp. [[neutrophils]] | |||
| Subtypes = | |||
| LMDDx = [[juvenile polyp]], [[mucosal prolapse]], [[adenomatous polyps]] | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[colon]], [[rectum]], others | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = +/-[[inflammatory bowel disease]] | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = | |||
| Bloodwork = | |||
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| Other = | |||
| ClinDDx = other types of polyps | |||
}} | |||
'''Inflammatory pseudopolyp''' is a benign polypoid lesion usually seen in the context of [[inflammatory bowel disease]]. | '''Inflammatory pseudopolyp''' is a benign polypoid lesion usually seen in the context of [[inflammatory bowel disease]]. | ||
Revision as of 10:21, 24 July 2013
| Inflammatory pseudopolyp | |
|---|---|
| Diagnosis in short | |
|
| |
| LM | polypoid shape, inflammatory cells - esp. neutrophils |
| LM DDx | juvenile polyp, mucosal prolapse, adenomatous polyps |
| Site | colon, rectum, others |
|
| |
| Clinical history | +/-inflammatory bowel disease |
| Clin. DDx | other types of polyps |
Inflammatory pseudopolyp is a benign polypoid lesion usually seen in the context of inflammatory bowel disease.
It is also referred to as inflammatory polyp.
General
- Not a true polyp.
- The label inflammatory pseudopolyp = inflammatory bowel disease (IBD).
- If there is no history of IBD... reconsider the diagnosis.
Microscopic
Features:
- Polypoid shape.
- Inflammation - esp. neutrophils - key feature.
Negatives:
- No nuclear atypia.
- May have focal nuclear hyperchromasia and nuclear enlargement.
- No dilated glands.
DDx:
Images:
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SIGMOID COLON POLYP, PERI-DIVERTICULAR, BIOPSY: - INFLAMMATORY PSEUDOPOLYP.
POLYP, DESCENDING COLON, BIOPSY: - INFLAMED POLYPOID FRAGMENT OF COLORECTAL-TYPE MUCOSA. -- NEGATIVE FOR DYSPLASIA.
Micro
The sections show a fragment of colorectal mucosa with focal ulceration, acute inflammation and a well-vascularized stroma with plump stromal cells. Occasional stromal cells have nuclear hyperchromasia.
See also
References
- ↑ Aust, DE.; Rüschoff, J. (Jul 2011). "[Polyps of the colorectum: non-neoplastic and non-hamartomatous].". Pathologe 32 (4): 297-302. doi:10.1007/s00292-011-1435-1. PMID 21607734.