Difference between revisions of "Chorangiosis"
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{{ Infobox diagnosis | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | | Name = {{PAGENAME}} | ||
| Image = Chorangiosis_-_high_mag.jpg | | Image = Chorangiosis_-_high_mag.jpg | ||
| Width = | | Width = | ||
| Caption = Chorangiosis. [[H&E stain]]. | | Caption = Chorangiosis. [[H&E stain]]. | ||
| Line 12: | Line 12: | ||
| Molecular = | | Molecular = | ||
| IF = | | IF = | ||
| Gross = | | Gross = not apparent on gross | ||
| Grossing = | | Grossing = | ||
| Site = [[placenta]] | | Site = [[placenta]] | ||
| Line 28: | Line 28: | ||
| ClinDDx = | | ClinDDx = | ||
}} | }} | ||
'''Chorangiosis''' is a relatively common [[placental pathology]]. | '''Chorangiosis''' is a relatively common [[placental pathology]]. It should '''not''' be confused with [[chorangioma]]. | ||
==General== | ==General== | ||
*Relative common among babies in ICU ~5%.<ref>URL: [http://www.bhj.org/journal/2009_5102_april/download/pg251-252.pdf http://www.bhj.org/journal/2009_5102_april/download/pg251-252.pdf]. Accessed on: 26 July 2011.</ref> | *Relative common among babies in ICU ~5%.<ref>URL: [http://www.bhj.org/journal/2009_5102_april/download/pg251-252.pdf http://www.bhj.org/journal/2009_5102_april/download/pg251-252.pdf]. Accessed on: 26 July 2011.</ref> | ||
*Increased fetal morbidity and mortality.<ref name=pmid22222282>{{Cite journal | last1 = Barut | first1 = A. | last2 = Barut | first2 = F. | last3 = Kandemir | first3 = NO. | last4 = Aktunc | first4 = E. | last5 = Arikan | first5 = I. | last6 = Harma | first6 = M. | last7 = Harma | first7 = MI. | last8 = Gun | first8 = BD. | title = Placental chorangiosis: the association with oxidative stress and angiogenesis. | journal = Gynecol Obstet Invest | volume = 73 | issue = 2 | pages = 141-51 | month = | year = 2012 | doi = 10.1159/000332370 | PMID = 22222282 }}</ref> | *Increased fetal morbidity and mortality.<ref name=pmid22222282>{{Cite journal | last1 = Barut | first1 = A. | last2 = Barut | first2 = F. | last3 = Kandemir | first3 = NO. | last4 = Aktunc | first4 = E. | last5 = Arikan | first5 = I. | last6 = Harma | first6 = M. | last7 = Harma | first7 = MI. | last8 = Gun | first8 = BD. | title = Placental chorangiosis: the association with oxidative stress and angiogenesis. | journal = Gynecol Obstet Invest | volume = 73 | issue = 2 | pages = 141-51 | month = | year = 2012 | doi = 10.1159/000332370 | PMID = 22222282 }}</ref> | ||
Latest revision as of 18:04, 12 February 2015
| Chorangiosis | |
|---|---|
| Diagnosis in short | |
 Chorangiosis. H&E stain. | |
|
| |
| LM | increased blood vessels in the terminal villi, diffuse |
| LM DDx | placental villous immaturity |
| Gross | not apparent on gross |
| Site | placenta |
|
| |
| Associated Dx | diabetes mellitus, gestational diabetes, smoking, IUGR |
Chorangiosis is a relatively common placental pathology. It should not be confused with chorangioma.
General
Associations:
- Maternal hypoxia:
Gross
- Usually not seen on gross pathology.
Microscopic
Features:
- Increased blood vessels in the terminal villi.
- Lesion not well circumscribed.
- Villi tend to be larger and have centrally placed blood vessels.[9]
Notes:
- Normal villi have up to five vascular channels.[7]
DDx:
Images
Chorangiosis - intermed. mag. (WC)
Chorangiosis - high mag. (WC)
Sign out
PLACENTA, UMBILICAL CORD AND FETAL MEMBRANES, CESAERIAN SECTION: - PLACENTAL DISC WITH CHORANGIOSIS. - THREE VESSEL UMBILICAL CORD WITHIN NORMAL LIMITS. - FETAL MEMBRANES WITHIN NORMAL LIMITS. COMMENT: Chorangiosis is a nonspecific finding that may be associated with diabetes, smoking or high altitude.
PLACENTA, UMBILICAL CORD AND FETAL MEMBRANES, CESAERIAN SECTION: - PLACENTAL DISC WITH: -- CHORANGIOSIS. -- FOCAL PERIVILLOUS FIBRIN DEPOSITION. - THREE VESSEL UMBILICAL CORD WITHIN NORMAL LIMITS. - FETAL MEMBRANES WITHIN NORMAL LIMITS. COMMENT: Chorangiosis is a nonspecific finding that may be associated with diabetes, smoking or high altitude.
Chorangiosis and meconium
PLACENTA, UMBILICAL CORD AND FETAL MEMBRANES, CESAERIAN SECTION: - THREE VESSEL UMBILICAL CORD WITHIN NORMAL LIMITS. - FETAL MEMBRANES WITHIN MECONIUM STAINING OF THE AMNION, NEGATIVE FOR CHORIOAMNIONITIS. - PLACENTAL DISC WITH: -- CHORANGIOSIS. -- FOCAL PERIVILLOUS FIBRIN DEPOSITION. COMMENT: Chorangiosis is a nonspecific finding that may be associated with diabetes, smoking or high altitude.
See also
References
- ↑ URL: http://www.bhj.org/journal/2009_5102_april/download/pg251-252.pdf. Accessed on: 26 July 2011.
- ↑ Barut, A.; Barut, F.; Kandemir, NO.; Aktunc, E.; Arikan, I.; Harma, M.; Harma, MI.; Gun, BD. (2012). "Placental chorangiosis: the association with oxidative stress and angiogenesis.". Gynecol Obstet Invest 73 (2): 141-51. doi:10.1159/000332370. PMID 22222282.
- ↑ Soma, H.; Watanabe, Y.; Hata, T. (1995). "Chorangiosis and chorangioma in three cohorts of placentas from Nepal, Tibet, and Japan.". Reprod Fertil Dev 7 (6): 1533-8. PMID 8743160.
- ↑ Daskalakis, G.; Marinopoulos, S.; Krielesi, V.; Papapanagiotou, A.; Papantoniou, N.; Mesogitis, S.; Antsaklis, A. (2008). "Placental pathology in women with gestational diabetes.". Acta Obstet Gynecol Scand 87 (4): 403-7. doi:10.1080/00016340801908783. PMID 18382864.
- ↑ Evers, IM.; Nikkels, PG.; Sikkema, JM.; Visser, GH.. "Placental pathology in women with type 1 diabetes and in a control group with normal and large-for-gestational-age infants.". Placenta 24 (8-9): 819-25. PMID 13129678.
- ↑ Altshuler, G. (Jan 1984). "Chorangiosis. An important placental sign of neonatal morbidity and mortality.". Arch Pathol Lab Med 108 (1): 71-4. PMID 6546343.
- ↑ 7.0 7.1 De La Ossa, MM.; Cabello-Inchausti, B.; Robinson, MJ. (Sep 2001). "Placental chorangiosis.". Arch Pathol Lab Med 125 (9): 1258. doi:10.1043/0003-9985(2001)1251258:PC2.0.CO;2. PMID 11520290. http://www.archivesofpathology.org/doi/full/10.1043/0003-9985%282001%29125%3C1258:PC%3E2.0.CO;2.
- ↑ URL: http://path.upmc.edu/cases/case655/dx.html. Accessed on: 28 January 2012.
- ↑ E. Latta. 26 July 2011.