Difference between revisions of "Chorangioma"

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#redirect [[Placenta#Chorangioma]]
{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Chorangioma_-_intermed_mag.jpg
| Width      =
| Caption    = Chorangioma. [[H&E stain]].
| Micro      = abundant capillaries surrounded by stroma
| Subtypes  =
| LMDDx      = [[chorangiosis]], [[chorangiomatosis]]
| Stains    =
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      = white or red lesion
| Grossing  =
| Site      = [[placenta]]
| Assdx      = +/-[[IUGR]], +/-fetal hydrops - if large
| Syndromes  =
| Clinicalhx =
| Signs      =
| Symptoms  =
| Prevalence = uncommon
| Bloodwork  =
| Rads      =
| Endoscopy  =
| Prognosis  =
| Other      =
| ClinDDx    =
}}
'''Chorangioma''' is an uncommon pathology of the [[placenta]] that is similar to a [[hemangioma]].
 
==General==
*[[Hamartoma]]-like growth in the placenta consisting of [[blood vessel]]s.<ref name=pmid20594143>{{cite journal |author=Amer HZ, Heller DS |title=Chorangioma and related vascular lesions of the placenta--a review |journal=Fetal Pediatr Pathol |volume=29 |issue=4 |pages=199–206 |year=2010 |pmid=20594143 |doi=10.3109/15513815.2010.487009 |url=}}</ref>
 
Epidemiology:
*Often benign/insignificant; large lesions (>4 cm<ref name=pmid20594143>{{cite journal |author=Amer HZ, Heller DS |title=Chorangioma and related vascular lesions of the placenta--a review |journal=Fetal Pediatr Pathol |volume=29 |issue=4 |pages=199–206 |year=2010 |pmid=20594143 |doi=10.3109/15513815.2010.487009 |url=}}</ref> or >5 cm<ref name=pmid21234259>{{cite journal |author=Lež C, Fures R, Hrgovic Z, Belina S, Fajdic J, Münstedt K |title=Chorangioma placentae |journal=Rare Tumors |volume=2 |issue=4 |pages=e67 |year=2010 |pmid=21234259 |pmc=3019602 |doi=10.4081/rt.2010.e67 |url=}}</ref>) or multiple lesions are significant.
*May be association with:
**Fetal maternal haemorrhage.
**[[Fetal hydrops]].
**[[IUGR]].
*Incidence: ~1 in 100 placentas.<ref name=pmid20594143/>
 
==Gross==
*White lesions.
**Occasionally red lesions.
 
==Microscopic==
Features:<ref name=pmid20594143/>
*Mass of capillaries - '''key feature'''.
*+/-High cellularity.
*+/-Degenerative changes.
 
Notes:
*Must be differentiated from [[chorangiomatosis]] (associated with preeclampsia & IUGR) and [[chorangiosis]] (associated with maternal [[diabetes mellitus]]).<ref name=pmid20594143/>
===Images===
<gallery>
Image:Chorangioma_-_high_mag.jpg | Chorangioma - high mag. (WC)
Image:Chorangioma_-_intermed_mag.jpg | Chorangioma - intermed. mag. (WC)
Image:Chorangioma_-_low_mag.jpg | Chorangioma - low mag. (WC)
</gallery>
 
==See also==
*[[Chorangiosis]].
*[[Chorangiomatosis]].
*[[Hemangioma]].
*[[Placenta]].
 
==References==
{{Reflist|2}}
 
[[Category:Placenta]]
[[Category:Diagnosis]]

Latest revision as of 13:16, 27 September 2013

Chorangioma
Diagnosis in short

Chorangioma. H&E stain.

LM abundant capillaries surrounded by stroma
LM DDx chorangiosis, chorangiomatosis
Gross white or red lesion
Site placenta

Associated Dx +/-IUGR, +/-fetal hydrops - if large
Prevalence uncommon

Chorangioma is an uncommon pathology of the placenta that is similar to a hemangioma.

General

Epidemiology:

  • Often benign/insignificant; large lesions (>4 cm[1] or >5 cm[2]) or multiple lesions are significant.
  • May be association with:
  • Incidence: ~1 in 100 placentas.[1]

Gross

  • White lesions.
    • Occasionally red lesions.

Microscopic

Features:[1]

  • Mass of capillaries - key feature.
  • +/-High cellularity.
  • +/-Degenerative changes.

Notes:

Images

See also

References

  1. 1.0 1.1 1.2 1.3 1.4 Amer HZ, Heller DS (2010). "Chorangioma and related vascular lesions of the placenta--a review". Fetal Pediatr Pathol 29 (4): 199–206. doi:10.3109/15513815.2010.487009. PMID 20594143.
  2. Lež C, Fures R, Hrgovic Z, Belina S, Fajdic J, Münstedt K (2010). "Chorangioma placentae". Rare Tumors 2 (4): e67. doi:10.4081/rt.2010.e67. PMC 3019602. PMID 21234259. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019602/.