Difference between revisions of "Inflammatory pseudopolyp"

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#redirect [[Gastrointestinal_tract_polyps#Inflammatory pseudopolyp]]
'''Inflammatory pseudopolyp''' is a benign polypoid lesion usually seen in the context of [[inflammatory bowel disease]].
 
It is also referred to as '''inflammatory polyp'''.
==General==
*Not a true polyp.
*The label ''inflammatory pseudopolyp'' = [[inflammatory bowel disease]] (IBD).
**If there is no history of IBD... reconsider the diagnosis.
 
==Microscopic==
Features:
*Polypoid shape.
*Inflammation - esp. neutrophils - '''key feature'''.
 
Negatives:
*No nuclear atypia.
**May have focal nuclear hyperchromasia and nuclear enlargement.
*No dilated glands.
 
DDx:
*[[Juvenile polyp]].
*[[Mucosal prolapse]].<ref name=pmid21607734>{{Cite journal  | last1 = Aust | first1 = DE. | last2 = Rüschoff | first2 = J. | title = [Polyps of the colorectum: non-neoplastic and non-hamartomatous]. | journal = Pathologe | volume = 32 | issue = 4 | pages = 297-302 | month = Jul | year = 2011 | doi = 10.1007/s00292-011-1435-1 | PMID = 21607734 }}</ref>
**[[Solitary rectal ulcer]].
 
Images:
*[http://www.humpath.com/spip.php?article8234&id_document=18554 Pseudopolyp (humpath.com)].
*[http://missinglink.ucsf.edu/lm/IDS_106_LowerGI/Lower_GI_histo_small/24-UC-pseudoplp.jpg Pseudopolyp (ucsf.edu)].
 
==Sign out==
<pre>
SIGMOID COLON POLYP, PERI-DIVERTICULAR, BIOPSY:
- INFLAMMATORY PSEUDOPOLYP.
</pre>
 
<pre>
POLYP, DESCENDING COLON, BIOPSY:
- INFLAMED POLYPOID FRAGMENT OF COLORECTAL-TYPE MUCOSA.
-- NEGATIVE FOR DYSPLASIA.
</pre>
 
===Micro===
The sections show a fragment of colorectal mucosa with focal ulceration, acute inflammation and a well-vascularized stroma with plump stromal cells.  Occasional stromal cells have nuclear hyperchromasia.
 
==See also==
*[[Gastrointestinal tract polyps]].
*[[Mucosal prolapse syndrome]].
*[[Colon]].
*[[Nasal polyps]].
 
==References==
{{Reflist|1}}


[[Category:Diagnosis]]
[[Category:Diagnosis]]

Revision as of 10:17, 24 July 2013

Inflammatory pseudopolyp is a benign polypoid lesion usually seen in the context of inflammatory bowel disease.

It is also referred to as inflammatory polyp.

General

  • Not a true polyp.
  • The label inflammatory pseudopolyp = inflammatory bowel disease (IBD).
    • If there is no history of IBD... reconsider the diagnosis.

Microscopic

Features:

  • Polypoid shape.
  • Inflammation - esp. neutrophils - key feature.

Negatives:

  • No nuclear atypia.
    • May have focal nuclear hyperchromasia and nuclear enlargement.
  • No dilated glands.

DDx:

Images:

Sign out

SIGMOID COLON POLYP, PERI-DIVERTICULAR, BIOPSY:
- INFLAMMATORY PSEUDOPOLYP.
POLYP, DESCENDING COLON, BIOPSY:
- INFLAMED POLYPOID FRAGMENT OF COLORECTAL-TYPE MUCOSA.
-- NEGATIVE FOR DYSPLASIA.

Micro

The sections show a fragment of colorectal mucosa with focal ulceration, acute inflammation and a well-vascularized stroma with plump stromal cells. Occasional stromal cells have nuclear hyperchromasia.

See also

References

  1. Aust, DE.; Rüschoff, J. (Jul 2011). "[Polyps of the colorectum: non-neoplastic and non-hamartomatous].". Pathologe 32 (4): 297-302. doi:10.1007/s00292-011-1435-1. PMID 21607734.