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Difference between revisions of "Uterine tumours"
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m
→Undifferentiated endometrial sarcoma: +IHC
(tweak) |
m (→Undifferentiated endometrial sarcoma: +IHC) |
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| Line 311: | Line 311: | ||
*Malignant. | *Malignant. | ||
*Rare. | *Rare. | ||
*This can be thought of as ''[[pleomorphic undifferentiated sarcoma]]'' in the [[uterus]]. | |||
===Microscopic=== | ===Microscopic=== | ||
| Line 328: | Line 329: | ||
*[[Rhabdomyosarcoma]]. | *[[Rhabdomyosarcoma]]. | ||
*[[Melanoma]]. | *[[Melanoma]]. | ||
===IHC=== | |||
Features:<ref>{{Cite journal | last1 = Abeler | first1 = VM. | last2 = Nenodovic | first2 = M. | title = Diagnostic immunohistochemistry in uterine sarcomas: a study of 397 cases. | journal = Int J Gynecol Pathol | volume = 30 | issue = 3 | pages = 236-43 | month = May | year = 2011 | doi = 10.1097/PGP.0b013e318200caff | PMID = 21464730 }}</ref> | |||
*SMA ~50% +ve. | |||
*Negative for smooth muscle markers: desmin, h-caldesmon. | |||
*Negative for skeletal muscle markers: Myf4, actin. | |||
*Usually negative: S100, HMB-45, CD117. | |||
=Weird stuff= | =Weird stuff= | ||