Difference between revisions of "Morphologic patterns"

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The article deals with '''morphologic patterns''' in pathology.  It is focused on light microscopy.
The article deals with '''morphologic patterns''' in [[pathology]].  It is focused on light microscopy.


=The big table of morphology=
''Histomorphology'' redirects here.
 
==The big table of morphology==
{| class="wikitable sortable" style="margin-left:auto;margin-right:auto"
{| class="wikitable sortable" style="margin-left:auto;margin-right:auto"
! Name of pattern
! Name of pattern
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! Image
! Image
|-
|-
| Hobnail
| [[Hobnail]]
| basement membrane area < area exposed to luminal surface
| basement membrane area < area exposed to luminal surface
| [[angiosarcoma]], clear cell carcinoma
| [[angiosarcoma]], clear cell carcinoma
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| [[File:Invasive_micropapillary_carcinoma_of_the_breast.jpg|thumb|center|150px|Micropapillary carcinoma. (WC)]]
| [[File:Invasive_micropapillary_carcinoma_of_the_breast.jpg|thumb|center|150px|Micropapillary carcinoma. (WC)]]
|-
|-
| Papillary  
| [[Papillary]]
| nipple-like projection with a fibrovascular core
| nipple-like projection with a fibrovascular core
| [[papillary thyroid carcinoma]]
| [[papillary thyroid carcinoma]]
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| [http://www.breastpathology.info/Sloane/Images/dcis/flat1-400.jpg flat DCIS 1 (breastpathology.info)],<ref name=sloane/> [http://www.breastpathology.info/Sloane/Images/dcis/flat2-400.jpg flat DCIS 2 (breastpathology.info)]<ref name=sloane>URL: [http://www.breastpathology.info/Sloane/dcis.html http://www.breastpathology.info/Sloane/dcis.html]. Accessed on: 8 August 2011.</ref>
| [http://www.breastpathology.info/Sloane/Images/dcis/flat1-400.jpg flat DCIS 1 (breastpathology.info)],<ref name=sloane/> [http://www.breastpathology.info/Sloane/Images/dcis/flat2-400.jpg flat DCIS 2 (breastpathology.info)]<ref name=sloane>URL: [http://www.breastpathology.info/Sloane/dcis.html http://www.breastpathology.info/Sloane/dcis.html]. Accessed on: 8 August 2011.</ref>
|-
|-
| Herring bone
| [[Herring bone]]
| like herring bone (technique) for climbing a hill in cross country skiing; books on a shelf, where they have partially fallen over -- on the one shelf to the left and the one below to the right
| like herring bone (technique) for climbing a hill in cross country skiing; books on a shelf, where they have partially fallen over -- on the one shelf to the left and the one below to the right
| [[fibrosarcoma]], [[synovial sarcoma]], [[MPNST]]
| [[fibrosarcoma]], [[synovial sarcoma]], [[MPNST]]
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|}
|}


=Patterns=
==Patterns==
==Hobnail pattern==
===Hobnail pattern===
*Basement membrane area < area exposed to luminal surface.
{{Main|Hobnail pattern}}
 
===Considerations===
Lung:
*[[Lung adenocarcinoma]].
*[[Atypical adenomatous hyperplasia of the lung]].
 
Breast:
*[[Lactational changes]].
 
Gynecology:
*[[Clear cell carcinoma of the endometrium]].
 
Kidney:
*[[Collecting duct carcinoma]].
*[[Acquired cystic disease-associated renal cell carcinoma]].
 
Other:
*[[Angiosarcoma]].
*Endothelial cells in [[granulation tissue]].
*[[Kimura disease]].


=See also=
==See also==
*[[Basics]].
*[[Basics]].


=References=
==References==
{{Reflist|1}}
{{Reflist|1}}


[[Category:Basics]]
[[Category:Basics]]
[[Category:Morphologic patterns]]

Latest revision as of 03:38, 31 March 2016

The article deals with morphologic patterns in pathology. It is focused on light microscopy.

Histomorphology redirects here.

The big table of morphology

Name of pattern Meaning DDx (incomplete/abbrev. list) Image
Hobnail basement membrane area < area exposed to luminal surface angiosarcoma, clear cell carcinoma
Angiosarcoma - very high mag. (WC/Nephron)
Storiform spiral appearance or cartwhell pattern[1] solitary fibrous tumour, DFSP, dermatofibroma, UPS
DFSP - very high mag. (WC/Nephron)
Fascicular the long axis of the (spindle) cells are perpendicular to one another in adjacent bundles of cells leiomyoma, leiomyosarcoma
Leiomyosarcoma - very high mag. (WC/Nephron)
Plexiform web-like formation[2] plexiform neurofibroma, MPNST, plexiform lesion of pulmonary hypertension plexiform lesion of Pulm. HTn (flickr.com)
Cribriform pierced with small holes[3] cribriform DCIS, cribriform HGPIN, cribriforming in a tubular adenoma with high-grade dysplasia, endometrioid endometrial carcinoma
Cribriform architecure (ADH) - very high mag. (WC/Nephron)
Solid or Sheeting no architecture - back-to-back cells with no pattern apparent / no spaces between cells solid DCIS, poorly-differentiated malignancy (carcinoma, sarcoma, lymphoma)
Sheeting in a Merkel cell carcinoma - high mag. (WC/Nephron)
Micropapillary nipple like projections without a fibrovascular core (papillary = nipple-like[4]) micropapillary DCIS, micropapillary HGPIN
Micropapillary carcinoma. (WC)
Papillary nipple-like projection with a fibrovascular core papillary thyroid carcinoma
Papillary RCC - high mag. (WC/Nephron)
Flat board-like, does not have a projection above the surface flat DCIS flat DCIS 1 (breastpathology.info),[5] flat DCIS 2 (breastpathology.info)[5]
Herring bone like herring bone (technique) for climbing a hill in cross country skiing; books on a shelf, where they have partially fallen over -- on the one shelf to the left and the one below to the right fibrosarcoma, synovial sarcoma, MPNST
MPNST - high mag.(WC/Nephron)
Trabecular or cords trabecula = little beam[6]; quasi-linear arrangement of cells normal liver lobule, Sertoli cell tumour
PTC tall cell variant - high mag. (WC/Nephron)
Nested (nesting) islands of cells with a circular outline neuroendocrine tumours
Neuroendocrine tumour - low mag. (WC/Nephron)
Biphasic / multiple patterns multiple patterns or cell types; e.g. spindle cells and epithelioid cells synovial sarcoma, malignant melanoma, pleomorphic adenoma, angiomyolipoma, chondroid syringoma
DSRCT - high mag. (WC/Nephron)

Patterns

Hobnail pattern

See also

References

  1. Storiform. dictionary.com. URL: http://dictionary.reference.com/browse/storiform. Accessed on: April 24, 2009.
  2. URL: http://www.mondofacto.com/facts/dictionary?plexiform. Accessed on: March 9, 2010.
  3. URL: http://dictionary.reference.com/browse/cribriform. Accessed on: 8 August 2011.
  4. URL: http://dictionary.reference.com/browse/papillary. Accessed on: 8 August 2011.
  5. 5.0 5.1 URL: http://www.breastpathology.info/Sloane/dcis.html. Accessed on: 8 August 2011.
  6. URL: http://dictionary.reference.com/browse/trabecula. Accessed on: 26 December 2010.