Difference between revisions of "Synaptophysin"
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Jensflorian (talk | contribs) (+neuropathology) |
Jensflorian (talk | contribs) (→Tumours: +more added) |
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* Substantia nigra | * Substantia nigra | ||
* Cerebellum system | * Cerebellum system | ||
* Olfactory bulb | * Olfactory bulb | ||
* Pineal gland | |||
* Adrenal gland | |||
* Langerhans islets | |||
==Tumours== | ==Tumours== | ||
* [[Ganglioglioma]] | * [[Ganglioglioma]]. | ||
* [[Medulloblastoma]] +/-ve. | * [[Medulloblastoma]] +/-ve. | ||
* [[Pituitary adenoma]] | * [[Pituitary adenoma]]. | ||
* [[Neurocytoma]]. | |||
* [[Paraganglioma]]. | |||
* [[Dysembryoplastic neuroepithelial tumour]]. | |||
* [[Atypical carcinoid]]. | |||
===Negative staining=== | ===Negative staining=== | ||
==See also== | ==See also== | ||
Latest revision as of 12:02, 8 April 2019
Synaptophysin staining in Atypical carcinoid.
Synaptophysin is the principal structural element of the walls of synaptic vesicles and thus a neuroendocrine marker.
Normal tissues
- Note: resists autolytic degradation (can be used 5 days post mortem).
- Marker of late onset (neuronal maturation).
Positive staining
- Cerebral cortex
- Hippocampus
- Corpus striatum,
- Globus pallidus
- Substantia nigra
- Cerebellum system
- Olfactory bulb
- Pineal gland
- Adrenal gland
- Langerhans islets
Tumours
- Ganglioglioma.
- Medulloblastoma +/-ve.
- Pituitary adenoma.
- Neurocytoma.
- Paraganglioma.
- Dysembryoplastic neuroepithelial tumour.
- Atypical carcinoid.