Difference between revisions of "Chorangioma"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Chorangioma_-_intermed_mag.jpg | |||
| Width = | |||
| Caption = Chorangioma. [[H&E stain]]. | |||
| Micro = abundant capillaries surrounded by stroma | |||
| Subtypes = | |||
| LMDDx = [[chorangiosis]] | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = white or red lesion | |||
| Grossing = | |||
| Site = [[placenta]] | |||
| Assdx = +/-[[IUGR]], +/-fetal hydrops - if large | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = | |||
| Other = | |||
| ClinDDx = | |||
}} | |||
'''Chorangioma''' is an uncommon pathology of the [[placenta]] that is similar to a [[hemangioma]]. | |||
==General== | |||
*[[Hamartoma]]-like growth in the placenta consisting of [[blood vessel]]s.<ref name=pmid20594143>{{cite journal |author=Amer HZ, Heller DS |title=Chorangioma and related vascular lesions of the placenta--a review |journal=Fetal Pediatr Pathol |volume=29 |issue=4 |pages=199–206 |year=2010 |pmid=20594143 |doi=10.3109/15513815.2010.487009 |url=}}</ref> | |||
Epidemiology: | |||
*Often benign/insignificant; large lesions (>4 cm<ref name=pmid20594143>{{cite journal |author=Amer HZ, Heller DS |title=Chorangioma and related vascular lesions of the placenta--a review |journal=Fetal Pediatr Pathol |volume=29 |issue=4 |pages=199–206 |year=2010 |pmid=20594143 |doi=10.3109/15513815.2010.487009 |url=}}</ref> or >5 cm<ref name=pmid21234259>{{cite journal |author=Lež C, Fures R, Hrgovic Z, Belina S, Fajdic J, Münstedt K |title=Chorangioma placentae |journal=Rare Tumors |volume=2 |issue=4 |pages=e67 |year=2010 |pmid=21234259 |pmc=3019602 |doi=10.4081/rt.2010.e67 |url=}}</ref>) or multiple lesions are significant. | |||
*May be association with: | |||
**Fetal maternal haemorrhage. | |||
**[[Fetal hydrops]]. | |||
**[[IUGR]]. | |||
*Incidence: ~1 in 100 placentas.<ref name=pmid20594143/> | |||
==Gross== | |||
*White lesions. | |||
**Occasionally red lesions. | |||
==Microscopic== | |||
Features:<ref name=pmid20594143/> | |||
*Mass of capillaries - '''key feature'''. | |||
*+/-High cellularity. | |||
*+/-Degenerative changes. | |||
Notes: | |||
*Must be differentiated from [[chorangiomatosis]] (associated with preeclampsia & IUGR) and chorangiosis (assoc. with maternal [[diabetes mellitus]]).<ref name=pmid20594143/> | |||
===Images=== | |||
<gallery> | |||
Image:Chorangioma_-_intermed_mag.jpg | Chorangioma - intermed. mag. (WC) | |||
Image:Chorangioma_-_low_mag.jpg | Chorangioma - low mag. (WC) | |||
</gallery> | |||
==See also== | |||
*[[Chorangiosis]]. | |||
*[[Chorangiomatosis]]. | |||
*[[Hemangioma]]. | |||
*[[Placenta]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Placenta]] | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
Revision as of 13:14, 27 September 2013
| Chorangioma | |
|---|---|
| Diagnosis in short | |
 Chorangioma. H&E stain. | |
|
| |
| LM | abundant capillaries surrounded by stroma |
| LM DDx | chorangiosis |
| Gross | white or red lesion |
| Site | placenta |
|
| |
| Associated Dx | +/-IUGR, +/-fetal hydrops - if large |
| Prevalence | uncommon |
Chorangioma is an uncommon pathology of the placenta that is similar to a hemangioma.
General
- Hamartoma-like growth in the placenta consisting of blood vessels.[1]
Epidemiology:
- Often benign/insignificant; large lesions (>4 cm[1] or >5 cm[2]) or multiple lesions are significant.
- May be association with:
- Fetal maternal haemorrhage.
- Fetal hydrops.
- IUGR.
- Incidence: ~1 in 100 placentas.[1]
Gross
- White lesions.
- Occasionally red lesions.
Microscopic
Features:[1]
- Mass of capillaries - key feature.
- +/-High cellularity.
- +/-Degenerative changes.
Notes:
- Must be differentiated from chorangiomatosis (associated with preeclampsia & IUGR) and chorangiosis (assoc. with maternal diabetes mellitus).[1]
Images
Chorangioma - intermed. mag. (WC)
Chorangioma - low mag. (WC)
See also
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Amer HZ, Heller DS (2010). "Chorangioma and related vascular lesions of the placenta--a review". Fetal Pediatr Pathol 29 (4): 199–206. doi:10.3109/15513815.2010.487009. PMID 20594143.
- ↑ Lež C, Fures R, Hrgovic Z, Belina S, Fajdic J, Münstedt K (2010). "Chorangioma placentae". Rare Tumors 2 (4): e67. doi:10.4081/rt.2010.e67. PMC 3019602. PMID 21234259. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019602/.