Worst pattern of invasion
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Worst pattern of invasion, abbreviated WPOI, is schema for classifying tumour morphologic patterns with the goal of predicting tumour behaviour.[1]
General
- WPOI is predictive of disease free survival in oral cancer.[1]
WPOI is described as five patterns - but generally divided into two (prognostic) groups:
- WPOI 1-4: better prognosis.
- WPOI 5: poor prognosis.
Definition of WPOI 5
WPOI 5 is defined as >=1 mm normal tissue between two tumour masses.[2]
See also
References
- ↑ 1.0 1.1 Shimizu S, Miyazaki A, Sonoda T, Koike K, Ogi K, Kobayashi JI, Kaneko T, Igarashi T, Ueda M, Dehari H, Miyakawa A, Hasegawa T, Hiratsuka H (2018). "Tumor budding is an independent prognostic marker in early stage oral squamous cell carcinoma: With special reference to the mode of invasion and worst pattern of invasion". PLoS One 13 (4): e0195451. doi:10.1371/journal.pone.0195451. PMC 5909609. PMID 29672550. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909609/.
- ↑ Sinha N, Rigby MH, McNeil ML, Taylor SM, Trites JR, Hart RD, Bullock MJ (May 2018). "The histologic risk model is a useful and inexpensive tool to assess risk of recurrence and death in stage I or II squamous cell carcinoma of tongue and floor of mouth". Mod Pathol 31 (5): 772–779. doi:10.1038/modpathol.2017.183. PMID 29393297.