Systemic lupus erythematosus lymphadenopathy

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Systemic lupus erythematosus lymphadenopathy
Diagnosis in short

Systemic lupus erythematosus lymphadenopathy. H&E stain.

LM lymph node with necrosis, hematoxylin bodies (in necrotic foci)
LM DDx Kikuchi disease
Site lymph node - see lymph node pathology

Associated Dx systemic lupus erythematosus
Clinical history +/-hx of systemic lupus erythematosus
Signs see systemic lupus erythematosus
Symptoms see systemic lupus erythematosus
Prevalence uncommon
Blood work see systemic lupus erythematosus
Clin. DDx lymphoma, other causes of lymphadenopathy
Treatment treatment for SLE

Systemic lupus erythematosus lymphadenopathy is a very rare lymph node pathology seen in systemic lupus erythematosus.


Clinical DDx:



  • Necrosis.
  • Hematoxylin bodies (in necrotic foci).
    • Dark blue irregular bodies on H&E.



See also


  1. Smith, LW.; Petri, M. (Oct 2013). "Diffuse lymphadenopathy as the presenting manifestation of systemic lupus erythematosus.". J Clin Rheumatol 19 (7): 397-9. doi:10.1097/RHU.0b013e3182a6a924. PMID 24048114.
  2. Kojima, M.; Nakamura, S.; Itoh, H.; Yoshida, K.; Asano, S.; Yamane, N.; Komatsumoto, S.; Ban, S. et al. (1997). "Systemic lupus erythematosus (SLE) lymphadenopathy presenting with histopathologic features of Castleman' disease: a clinicopathologic study of five cases.". Pathol Res Pract 193 (8): 565-71. PMID 9406250.