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Difference between revisions of "Invasive breast cancer"
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Invasive breast cancer (view source)
Revision as of 01:48, 16 November 2011
, 01:48, 16 November 2011→Subtyping breast cancer: +molecular classification
m (→Microscopic) |
(→Subtyping breast cancer: +molecular classification) |
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=Breast IHC= | =Breast IHC= | ||
==Molecular classification of ''invasive carcinoma no special type''== | |||
A molecular classification:<ref name=Ref_PCPBoD8_547>{{Ref PCPBoD8|547}}</ref> | |||
{| class="wikitable sortable" style="margin-left:auto;margin-right:auto" | |||
! Type | |||
! Percentage | |||
! IHC | |||
! Histology | |||
! Prognosis/clinical | |||
|- | |||
| Luminal A | |||
| ~45% | |||
| ER+ PR+ HER2- | |||
| well-differentiated | |||
| good, chemo resistant | |||
|- | |||
| Luminal B | |||
| 17% | |||
| ER+ PR+ HER2+ | |||
| high grade | |||
| poor, +/- chemo responsive | |||
|- | |||
| Normal breast-like | |||
| ~8% | |||
| ER+ PR+ (?) HER2- | |||
| well-differentiated | |||
| good | |||
|- | |||
| Basal-like | |||
| ~20% | |||
| ER- PR- HER2- | |||
| poorly differentiated | |||
| aggressive, may have good chemo response | |||
|- | |||
| HER2 positive | |||
| ~10% | |||
| ER- PR- (?) HER2+ | |||
| poorly differentiated | |||
| poor | |||
|} | |||
==Subtyping breast cancer== | ==Subtyping breast cancer== | ||