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Difference between revisions of "P16"
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</gallery> | </gallery> | ||
===Penile cancer=== | ===Penile cancer=== | ||
*p16 is considered surrogate for HPV and ''block-type positivity'' is considered indicative of HPV.<ref name=pmid36221864>{{cite journal |authors=Menon S, Moch H, Berney DM, Cree IA, Srigley JR, Tsuzuki T, Compérat E, Hartmann A, Netto G, Rubin MA, Gill AJ, Turajlic S, Tan PH, Raspollini MR, Tickoo SK, Amin MB |title=WHO 2022 classification of penile and scrotal cancers: updates and evolution |journal=Histopathology |volume=82 |issue=4 |pages=508–520 |date=March 2023 |pmid=36221864 |doi=10.1111/his.14824 |url=}}<ref> | *p16 is considered surrogate for HPV and ''block-type positivity'' is considered indicative of HPV.<ref name=pmid36221864>{{cite journal |authors=Menon S, Moch H, Berney DM, Cree IA, Srigley JR, Tsuzuki T, Compérat E, Hartmann A, Netto G, Rubin MA, Gill AJ, Turajlic S, Tan PH, Raspollini MR, Tickoo SK, Amin MB |title=WHO 2022 classification of penile and scrotal cancers: updates and evolution |journal=Histopathology |volume=82 |issue=4 |pages=508–520 |date=March 2023 |pmid=36221864 |doi=10.1111/his.14824 |url=}}</ref> | ||
*An older meta-analysis shows that p16 staining criteria are not firmly established. | *An older meta-analysis shows that p16 staining criteria are not firmly established. | ||