Difference between revisions of "Molecular pathology"

Molecular pathology (view source)

484 bytes added , 13:30, 10 May 2011

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 ====Karyotyping====
 *Metaphase nuclei.
+*Chromosomes are identified by:
+**Size (chromosome 1 = largest, chromosome 22 = smallest).
+**Position of centromere.
+**Banding pattern - use special stains:
+***Several different techniques (stains) are used:<ref>URL: [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC355922/ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC355922/]. Accessed on: 10 May 2011.</ref>
+****Examples: C-banding (C=constitutive heterchromatin), G-banding (G=Giemsa), Q-banding (Q=Quinacrine), R-banding (R=reverse).
 Image: