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Difference between revisions of "Other CNS embryonal tumours"
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==General== | ==General== | ||
Other CNS embryonal tumours are a group of primitive neuroeptithelial tumors that are to be classified in distinct molecular groups in the future. | Other CNS embryonal tumours are a group of primitive neuroeptithelial tumors that are to be classified in distinct molecular groups in the future. | ||
Currently it is a exlcusion criteria encompassing four subgroups | |||
*CNS neuroblastomas | |||
*CNS ganglioneuroblastomas. | |||
** often characterized by FOXR2 fusions: ''CNS neuroblastoma with FOXR2 activation (NB‐FOXR2)'' | |||
*CNS medulloepithelioma. | |||
** but absence of C19MC alteration, otherwise classified as [[ETMR]] | |||
* CNS embryonal tumour, NOS | |||
** Similarities to astroblastoma: ''High‐grade neuroepithelial tumours with MN1 alteration (HGNET‐MN1)'' | |||
** NUTM1-positive IHC: ''Ewing's sarcoma family tumour with CIC alteration (EFT‐CIC)'' | |||
** BCOR-positive IHC: ''HGNET BCOR‐altered neuroepithelial tumours'' | |||