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Difference between revisions of "Parathyroid adenoma"
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Parathyroid adenoma (view source)
Revision as of 03:19, 11 September 2015
, 03:19, 11 September 2015+infobox
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Parathyroid adenoma intermed mag.jpg | |||
| Width = | |||
| Caption = Chief cell parathyroid adenoma (left of image) and unremarkable parathyroid gland (right of image). [[H&E stain]]. (WC) | |||
| Synonyms = | |||
| Micro = | |||
| Subtypes = | |||
| LMDDx = [[parathyroid hyperplasia]], [[parathyroid carcinoma]], [[lymph node]], [[thyroid gland]] | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[parathyroid gland]] ([[head and neck pathology|neck]]/[[mediastinum]]) | |||
| Assdx = | |||
| Syndromes = [[MEN 1|multiple endocrine neoplasia 1]], [[MEN 2A|multiple endocrine neoplasia 2A]] | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = | |||
| Bloodwork = increased parathyroid hormone, serum calcium increased | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = nodule (lymph node, other tumours), hyperparathyroidism ([[parathyroid hyperplasia]], [[parathyroid carcinoma]]), DDx of [[hypercalcemia]] | |||
| Tx = removal | |||
}} | |||
'''Parathyroid adenoma''' is a common benign pathology of the [[parathyroid gland]]. | '''Parathyroid adenoma''' is a common benign pathology of the [[parathyroid gland]]. | ||
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*[[Clinical diagnosis]]. | *[[Clinical diagnosis]]. | ||
*Most common cause of [[primary hyperparathyroidism]].<ref name=Ref_PBoD8_1127>{{Ref PBoD8|1127}}</ref> | *Most common cause of [[primary hyperparathyroidism]].<ref name=Ref_PBoD8_1127>{{Ref PBoD8|1127}}</ref> | ||
*May be associated with [[MEN 1]] and [[MEN 2A]]. | *May be associated with [[MEN 1]] and [[MEN 2A]]. | ||
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#*Uncommon.<ref name=pmid15579742>{{Cite journal | last1 = Fleischer | first1 = J. | last2 = Becker | first2 = C. | last3 = Hamele-Bena | first3 = D. | last4 = Breen | first4 = TL. | last5 = Silverberg | first5 = SJ. | title = Oxyphil parathyroid adenoma: a malignant presentation of a benign disease. | journal = J Clin Endocrinol Metab | volume = 89 | issue = 12 | pages = 5948-51 | month = Dec | year = 2004 | doi = 10.1210/jc.2004-1597 | PMID = 15579742 }}</ref> | #*Uncommon.<ref name=pmid15579742>{{Cite journal | last1 = Fleischer | first1 = J. | last2 = Becker | first2 = C. | last3 = Hamele-Bena | first3 = D. | last4 = Breen | first4 = TL. | last5 = Silverberg | first5 = SJ. | title = Oxyphil parathyroid adenoma: a malignant presentation of a benign disease. | journal = J Clin Endocrinol Metab | volume = 89 | issue = 12 | pages = 5948-51 | month = Dec | year = 2004 | doi = 10.1210/jc.2004-1597 | PMID = 15579742 }}</ref> | ||
#Mixed. | #Mixed. | ||
==Gross== | |||
*One parathyroid is big... the others are small. | |||
==Microscopic== | ==Microscopic== | ||