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Difference between revisions of "Astrocytoma"
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=Common= | =Common= | ||
==Pilocytic astrocytoma== | ==Pilocytic astrocytoma== | ||
* Benign, cystic, infratentorial. | |||
* Classic childhood tumor, surgically resectable. | |||
* Variant: [[Pilomyxoid astrocytoma]] | |||
{{Main|Pilocytic astrocytoma}} | {{Main|Pilocytic astrocytoma}} | ||
==Diffuse astrocytoma== | ==Diffuse astrocytoma== | ||
* Grade II | * Grade II astrocytic tumors typically seen in adults. | ||
* | * Usually show progression to glioblastoma. | ||
{{Main|Diffuse astrocytoma}} | |||
==Anaplastic astrocytoma== | |||
* Grade III astrocytic tumors typically seen in adults. | |||
* Lacks endothelial proliferations and necrosis of glioblastoma. | |||
{{Main|Anaplastic astrocytoma}} | |||
==Glioblastoma== | ==Glioblastoma== | ||
* Most common malignant brain tumor peaking around 65 years. | |||
* Prognosis very poor. | |||
* Variant: [[Giant cell glioblastoma]] | |||
* Variant: [[Gliosarcoma]] | |||
{{Main|Glioblastoma}} | {{Main|Glioblastoma}} | ||
=Uncommon= | =Uncommon= | ||
==Subependymal giant cell astrocytoma== | ==Subependymal giant cell astrocytoma== | ||
* Intraventricular benign tumor of adolescents. | |||
* Assoicated with [[Tuberous sclerosis]]. | |||
{{Main|Subependymal giant cell astrocytoma}} | {{Main|Subependymal giant cell astrocytoma}} | ||
==Pleomorphic xanthroastrocytoma | ==Pleomorphic xanthroastrocytoma (PXA)== | ||
* Kids & young adults usually with good prognosis. | |||
* Large lipidized cells mimicking a malignant tumor | |||
*Kids & young adults | {{Main|Pleomorphic xanthoastrocytoma}} | ||
*Large cells | |||
==Gliomatosis cerebri== | ==Gliomatosis cerebri== | ||
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* More than 3 lobes have to be involved, us. bilateral (radiology). | * More than 3 lobes have to be involved, us. bilateral (radiology). | ||
* biologic behaviour corresponds to WHO III (ICD-O: 9381/3) | * biologic behaviour corresponds to WHO III (ICD-O: 9381/3) | ||
==H3.3 K27M mutated glioma of the midline== | ==H3.3 K27M mutated glioma of the midline== | ||
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====Images==== | ====Images==== | ||
<gallery> | <gallery> | ||
Image:Gliosarcoma_Histopathology_200x_EVG.jpg | Gliosarcoma - | Image:Gliosarcoma_Histopathology_200x_EVG.jpg | Gliosarcoma - elastica van Giesson. (WC) | ||
</gallery> | </gallery> | ||
www: | www: | ||
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*SMA +ve. | *SMA +ve. | ||
*Factor VIII +ve. | *Factor VIII +ve. | ||
==Gliofibroma== | |||
* Very rare indolent tumor in children <ref>{{Cite journal | last1 = Deb | first1 = P. | last2 = Sarkar | first2 = C. | last3 = Garg | first3 = A. | last4 = Singh | first4 = VP. | last5 = Kale | first5 = SS. | last6 = Sharma | first6 = MC. | title = Intracranial gliofibroma mimicking a meningioma: a case report and review of literature. | journal = Clin Neurol Neurosurg | volume = 108 | issue = 2 | pages = 178-86 | month = Feb | year = 2006 | doi = 10.1016/j.clineuro.2004.11.021 | PMID = 16412839 }}</ref> | |||
* Usually not dura-based (DD: Desmoplastic infantile astrocytoma) | |||
* Glial tumor with non-neoplastic fibromatous component. | |||
=See also= | =See also= | ||