Difference between revisions of "Invasive breast cancer"

Jump to navigation Jump to search

Invasive breast cancer (view source)

Revision as of 07:54, 14 April 2015

4,639 bytes removed ,  07:54, 14 April 2015
→‎Adenoid cystic carcinoma of the breast: split out
(+image)
Line 445: Line 445:
==Adenoid cystic carcinoma of the breast==
==Adenoid cystic carcinoma of the breast==
*[[AKA]] ''breast adenoid cystic carcinoma''.
*[[AKA]] ''breast adenoid cystic carcinoma''.
===General===
{{Main|Adenoid cystic carcinoma of the breast}}
*Like tumour of the [[salivary gland]].
*Very rare <0.1% of breast malignancies.<ref name=pmid22154460/>
*Good prognosis.<ref name=pmid22154460>{{Cite journal  | last1 = Boujelbene | first1 = N. | last2 = Khabir | first2 = A. | last3 = Boujelbene | first3 = N. | last4 = Jeanneret Sozzi | first4 = W. | last5 = Mirimanoff | first5 = RO. | last6 = Khanfir | first6 = K. | title = Clinical review - Breast adenoid cystic carcinoma. | journal = Breast | volume =  | issue =  | pages =  | month = Dec | year = 2011 | doi = 10.1016/j.breast.2011.11.006 | PMID = 22154460 }}</ref>
 
===Microscopic===
:See: ''[[Adenoid cystic carcinoma]]'' article.
 
===IHC===
*One of the 'good prognosis' triple negative breast cancers - ER, PR and HER2 negative<ref>{{Cite journal  | last1 = Azoulay | first1 = S. | last2 = Laé | first2 = M. | last3 = Fréneaux | first3 = P. | last4 = Merle | first4 = S. | last5 = Al Ghuzlan | first5 = A. | last6 = Chnecker | first6 = C. | last7 = Rosty | first7 = C. | last8 = Klijanienko | first8 = J. | last9 = Sigal-Zafrani | first9 = B. | title = KIT is highly expressed in adenoid cystic carcinoma of the breast, a basal-like carcinoma associated with a favorable outcome. | journal = Mod Pathol | volume = 18 | issue = 12 | pages = 1623-31 | month = Dec | year = 2005 | doi = 10.1038/modpathol.3800483 | PMID = 16258515 }}</ref>
*Basal-like breast cancer - p63 and CK5/6 positive<ref>{{Cite journal  | last1 = Azoulay | first1 = S. | last2 = Laé | first2 = M. | last3 = Fréneaux | first3 = P. | last4 = Merle | first4 = S. | last5 = Al Ghuzlan | first5 = A. | last6 = Chnecker | first6 = C. | last7 = Rosty | first7 = C. | last8 = Klijanienko | first8 = J. | last9 = Sigal-Zafrani | first9 = B. | title = KIT is highly expressed in adenoid cystic carcinoma of the breast, a basal-like carcinoma associated with a favorable outcome. | journal = Mod Pathol | volume = 18 | issue = 12 | pages = 1623-31 | month = Dec | year = 2005 | doi = 10.1038/modpathol.3800483 | PMID = 16258515 }}</ref>
CD117 positive<ref>{{Cite journal  | last1 = Azoulay | first1 = S. | last2 = Laé | first2 = M. | last3 = Fréneaux | first3 = P. | last4 = Merle | first4 = S. | last5 = Al Ghuzlan | first5 = A. | last6 = Chnecker | first6 = C. | last7 = Rosty | first7 = C. | last8 = Klijanienko | first8 = J. | last9 = Sigal-Zafrani | first9 = B. | title = KIT is highly expressed in adenoid cystic carcinoma of the breast, a basal-like carcinoma associated with a favorable outcome. | journal = Mod Pathol | volume = 18 | issue = 12 | pages = 1623-31 | month = Dec | year = 2005 | doi = 10.1038/modpathol.3800483 | PMID = 16258515 }}</ref>
 
DDx:
*Cribriform [[DCIS]].
*Invasive cribriform carcinoma.
*[[Collagenous spherulosis]].
 
===Images===
*[http://path.upmc.edu/cases/case140.html Adenoid cystic carcinoma of the breast (upmc.edu)].>>
<gallery>
Image:Breast AdenoidCysticCarcinoma 2 LP CTR.jpg|Breast Adenoid Cystic Carcinoma - low power (SKB)
Image:Breast AdenoidCysticCarcinoma 2 MP CTR (3).jpg|Breast Adenoid Cystic Carcinoma - medium power (SKB)
Image:Breast AdenoidCysticCarcinoma 2 MP2 CTR.jpg|Breast Adenoid Cystic Carcinoma - medium power (SKB)
Image:Breast AdenoidCysticCarcinoma 2 MP2 CTR.jpg|Breast Adenoid Cystic Carcinoma - medium power (SKB)
Image:Breast AdenoidCysticCarcinoma 2 MP CTR.jpg|Breast Adenoid Cystic Carcinoma - medium power (SKB)
Image:Breast AdenoidCysticCarcinoma MP CTR.jpg|Breast Adenoid Cystic Carcinoma - medium power (SKB)
Image:Breast AdenoidCysticCarcinoma MP CTR (2).jpg|Breast Adenoid Cystic Carcinoma - medium power (SKB)
Image:Breast AdenoidCysticCarcinoma 2 HP CTR (2).jpg|Breast Adenoid Cystic Carcinoma - high power (SKB)
Image:Breast AdenoidCysticCarcinoma 2 HP CTR.jpg|Breast Adenoid Cystic Carcinoma - high power (SKB)
Image:Breast AdenoidCysticCarcinoma 2 HP3 CTR.jpg|Breast Adenoid Cystic Carcinoma - high power (SKB)
Image:Breast AdenoidCysticCarcinoma 2 HP2 CTR.jpg|Breast Adenoid Cystic Carcinoma - high power (SKB)
Image:Breast AdenoidCysticCarcinoma SolidType LP 14BR***.jpg|Breast - Adenoid Cystic Carcinoma -  Solid Type - Low power (SKB)
Image:Breast AdenoidCysticCarcinoma SolidType 14BR***.jpg|Breast - Adenoid Cystic Carcinoma -  Solid Type - medium power - Aggregates of basaloid cells without tubule or cyst formation.  (SKB)
Image:Breast AdenoidCysticCarcinoma SolidType HP 14BR***.jpg|Breast - Adenoid Cystic Carcinoma -  Solid Type - High power (SKB)
Image:Breast AdenoidCysticCarcinoma SolidType 2 14BR***.jpg|Breast Adenoid Cystic Carcinoma - Solid Type - high power (SKB)
</gallery>
 
===Other Resources===
Pathology Outlines [http://www.pathologyoutlines.com/topic/breastmalignantadenoidcystic.html]


==Intracystic papillary carcinoma of the breast==
==Intracystic papillary carcinoma of the breast==
Michael
48,830

edits

Retrieved from "https://librepathology.org/wiki/Special:MobileDiff/37574"

Navigation menu