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(→Invasive versus non-invasive: tweak) |
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===Invasive versus non-invasive=== | ===Invasive versus non-invasive=== | ||
Myoepithelial markers - typically lost in invasive carcinoma:<ref | Myoepithelial markers - typically lost in invasive carcinoma:<ref>{{Ref Lester3|88}}</ref> | ||
{| class="wikitable sortable" | {| class="wikitable sortable" | ||
!Stain | !Stain | ||
!Location | |||
!Notes | !Notes | ||
|- | |- | ||
| p63 | | p63 | ||
| up to 10% of invasive | | nuclear | ||
| up to 10% of invasive tumours +ve<ref name=Ref_BP276>{{Ref BP|276}}</ref> | |||
|- | |- | ||
| | | Smooth muscle actin (SMA) | ||
| cytoplasmic | |||
| stains myofibroblasts & blood vessels | | stains myofibroblasts & blood vessels | ||
|- | |- | ||
| Calponin | | Calponin | ||
| cytoplasmic | |||
| stains myofibroblasts & blood vessels | | stains myofibroblasts & blood vessels | ||
|- | |- | ||
| Smooth muscle myosin <br>heavy chain ( | | Smooth muscle myosin <br>heavy chain (SMM-HC) | ||
| cytoplasmic | | cytoplasmic | ||
| stains myofibroblasts & blood vessels | |||
|} | |} | ||
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