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(→Castleman disease: +images) |
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===Microscopic=== | ===Microscopic=== | ||
Hyaline-vascular variant (HVV) | ====Hyaline-vascular variant (HVV)==== | ||
Features:<ref>URL: [http://www.ispub.com/journal/the_internet_journal_of_otorhinolaryngology/volume_9_number_2_11/article/a_rare_case_of_castleman_s_disease_presenting_as_cervical_neck_mass.html http://www.ispub.com/journal/the_internet_journal_of_otorhinolaryngology/volume_9_number_2_11/article/a_rare_case_of_castleman_s_disease_presenting_as_cervical_neck_mass.html]. Accessed on: 15 June 2010.</ref><ref name=Ref_ILNP236>{{Ref ILNP|236}}</ref> | |||
*Pale concentric (expanded) mantle zone lymphocytes - '''key feature'''. | *Pale concentric (expanded) mantle zone lymphocytes - '''key feature'''. | ||
**"Regressed follicles" - germinal center (pale area) is small. | **"Regressed follicles" - germinal center (pale area) is small. | ||
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*[http://commons.wikimedia.org/wiki/File:Castleman_disease_-_intermed_mag.jpg CD HVV - showing expanded mantle zone - intermed. mag. (WC)]. | *[http://commons.wikimedia.org/wiki/File:Castleman_disease_-_intermed_mag.jpg CD HVV - showing expanded mantle zone - intermed. mag. (WC)]. | ||
Plasma cell variant | ====Plasma cell variant==== | ||
Features:<ref name=Ref_ILNP236>{{Ref ILNP|236}}</ref> | |||
*Interfollicular sheets of plasma cells - '''key feature'''. | *Interfollicular sheets of plasma cells - '''key feature'''. | ||
*Active germinal centers - mitoses present. | *Active germinal centers - mitoses present. |
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