Difference between revisions of "Invasive breast cancer"

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===Microscopic===
===Microscopic===
Features:
Features:
*Mucin producing glands.
*Malignant mucin producing glands.
**Should comprise >90% of the tumour.<ref name=pmid22006768>{{Cite journal  | last1 = Dogan | first1 = E. | last2 = Aksoy | first2 = S. | last3 = Dizdar | first3 = O. | last4 = Arslan | first4 = C. | last5 = Dede | first5 = DS. | last6 = Ozisik | first6 = Y. | last7 = Altundag | first7 = K. | title = Pure mucinous carcinoma of the breast: a single center experience. | journal = J BUON | volume = 16 | issue = 3 | pages = 565-7 | month =  | year =  | doi =  | PMID = 22006768 }}</ref>
**Mucinous component should comprise >90% of the tumour.<ref name=pmid22006768>{{Cite journal  | last1 = Dogan | first1 = E. | last2 = Aksoy | first2 = S. | last3 = Dizdar | first3 = O. | last4 = Arslan | first4 = C. | last5 = Dede | first5 = DS. | last6 = Ozisik | first6 = Y. | last7 = Altundag | first7 = K. | title = Pure mucinous carcinoma of the breast: a single center experience. | journal = J BUON | volume = 16 | issue = 3 | pages = 565-7 | month =  | year =  | doi =  | PMID = 22006768 }}</ref>
**Cells should float in the mucin - '''key feature'''.
**Glands typically have irregular edges.
**+/-Vessels within the mucin pools.
 
DDx:
*[[DCIS]] with a mucinous component.
**Mucin has homogenous appearance, mucin lacks vascularization, mucin pools have a regular border.


Note:
Note:
*The amount of mucinous component to call ''[[mucinous carcinoma]]'' varies by anatomical site.
*The amount of mucinous component to call ''[[mucinous carcinoma]]'' varies by anatomical site.
===IHC===
*ER +ve.
*PR +ve.
*HER2 -ve.


==Adenoid cystic carcinoma of the breast==
==Adenoid cystic carcinoma of the breast==
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