Difference between revisions of "Invasive breast cancer"

Invasive breast cancer (view source)

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 ===Microscopic===
 Features:
-*Cohesive cells.
+*Atypical cells:
+**Usually >2x RBC diameter.
+**Nucleoli common.
 **Forming ducts ''or'' sheets.
-*Nuclear pleomorphism.
+**+/-Mitoses.
-**Nucleoli common.
+**+/-Necrosis.
+*Evidence of invasion:
+**Atypical nucleus adjacent to adipocyte - '''diagnostic'''.
+**"Infiltrative" pattern:
+***Small glands of variable size within desmoplastic stroma.
+***Glands lined by a single layer of cells.
+DDx:
+*[[DCIS]].
+*[[Invasive lobular carcinoma]].
 ===IHC===