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Difference between revisions of "Invasive breast cancer"
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Invasive breast cancer (view source)
Revision as of 19:59, 27 November 2011
, 19:59, 27 November 2011→HER2 scoring
| Line 153: | Line 153: | ||
|} | |} | ||
Notes: | Notes 1: | ||
*Normal breast epithelial cells do not stain with HER2. | *Normal breast epithelial cells do not stain with HER2. | ||
*Evaluated on the invasive component. | *Evaluated on the invasive component. | ||
| Line 162: | Line 162: | ||
{| class="wikitable" | {| class="wikitable" | ||
| '''Result''' | | '''Result''' | ||
| ''' | | '''Ratio criteria''' | ||
| '''Gene copy number criteria''' | |||
|- | |- | ||
| Positive | | Positive | ||
| >2.2 HER2/CEP17 | | >2.2 HER2/CEP17 | ||
| >6.0 copies of HER2/cell | |||
|- | |- | ||
| Equivocal | | Equivocal | ||
| 1.8-2.2 HER2/CEP17 | | 1.8-2.2 HER2/CEP17 | ||
| 4.0-6.0 copies of HER2/cell | |||
|- | |- | ||
| Negative | | Negative | ||
| <1.8 HER2/CEP17 | | <1.8 HER2/CEP17 | ||
| <4.0 copies of HER2/cell | |||
|} | |} | ||
Notes 2: | |||
*Can be called ''positive'' based on either ''ratio criteria'' or ''gene copy number criteria''. | |||
===Clinical=== | ===Clinical=== | ||