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Difference between revisions of "Invasive breast cancer"
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Invasive breast cancer (view source)
Revision as of 19:47, 27 November 2011
, 19:47, 27 November 2011→HER2 scoring{{Ref Lester|241-2}}: more
m (→General: bold Rosen) |
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*Normal breast epithelial cells have a patchy staining for ER and PR. | *Normal breast epithelial cells have a patchy staining for ER and PR. | ||
*Evaluated on the invasive component. | *Evaluated on the invasive component. | ||
===HER2 scoring<ref name=Ref_Lester241-2>{{Ref Lester|241-2}}</ref>= | ===HER2 scoring=== | ||
Immunohistochemical based testing:<ref name=Ref_Lester241-2>{{Ref Lester|241-2}}</ref><ref name=Lester3_87>{{Ref Lester3|87}}</ref> | |||
{| class="wikitable" | {| class="wikitable" | ||
| '''Score''' | | '''Score''' | ||
| Line 157: | Line 158: | ||
*SISH = silver [[in situ hybridization]]. | *SISH = silver [[in situ hybridization]]. | ||
*FISH = fluorescence in situ hybridization. | *FISH = fluorescence in situ hybridization. | ||
ISH based testing:<ref name=Lester3_87>{{Ref Lester3|87}}</ref> | |||
{| class="wikitable" | |||
| '''Result''' | |||
| '''Findings''' | |||
|- | |||
| Positive | |||
| >2.2 HER2/CEP17 | |||
|- | |||
| Equivocal | |||
| 1.8-2.2 HER2/CEP17 | |||
|- | |||
| Negative | |||
| <1.8 HER2/CEP17 | |||
|} | |||
===Clinical=== | ===Clinical=== | ||