From Libre Pathology
Jump to: navigation, search

MICROTUBULE-ASSOCIATED PROTEIN 2, abbreviated MAP2,[1] is a common immunostain used in neuropathology and pulmonary pathology. It's expression is associated with neuronal, glial or neuroendocrine differentiation



See also


  1. Online 'Mendelian Inheritance in Man' (OMIM) 157130
  2. Kalcheva, N.; Albala, J.; O'Guin, K.; Rubino, H.; Garner, C.; Shafit-Zagardo, B. (Nov 1995). "Genomic structure of human microtubule-associated protein 2 (MAP-2) and characterization of additional MAP-2 isoforms.". Proc Natl Acad Sci U S A 92 (24): 10894-8. PMID 7479905.
  3. Blümcke, I.; Becker, AJ.; Normann, S.; Hans, V.; Riederer, BM.; Krajewski, S.; Wiestler, OD.; Reifenberger, G. (Oct 2001). "Distinct expression pattern of microtubule-associated protein-2 in human oligodendrogliomas and glial precursor cells.". J Neuropathol Exp Neurol 60 (10): 984-93. PMID 11589429.
  4. Duggal, N.; Hammond, RR. (Mar 2002). "Nestin expression in ganglioglioma.". Exp Neurol 174 (1): 89-95. doi:10.1006/exnr.2001.7838. PMID 11869037.
  5. Wharton, SB.; Chan, KK.; Whittle, IR. (Mar 2002). "Microtubule-associated protein 2 (MAP-2) is expressed in low and high grade diffuse astrocytomas.". J Clin Neurosci 9 (2): 165-9. doi:10.1054/jocn.2001.1055. PMID 11922706.
  6. Liu, Y.; Saad, RS.; Shen, SS.; Silverman, JF. (Mar 2003). "Diagnostic value of microtubule-associated protein-2 (MAP-2) for neuroendocrine neoplasms.". Adv Anat Pathol 10 (2): 101-6. PMID 12605092.
  7. Duggal, N.; Iskander, S.; Hammond, RR.. "MAP2 and nestin co-expression in dysembryoplastic neuroepithelial tumors.". Clin Neuropathol 22 (2): 57-65. PMID 12670051.
  8. Zhou, DM.; Sun, Y.; Li, XH. (May 2013). "[Diagnostic value of microtubule-associated protein-2 in small cell lung carcinoma: an analysis of 240 biopsy cases].". Zhonghua Bing Li Xue Za Zhi 42 (5): 321-4. PMID 24004589.
  9. Liu, Y.; Sturgis, CD.; Grzybicki, DM.; Jasnosz, KM.; Olson, PR.; Tong, M.; Dabbs, DD.; Raab, SS. et al. (Sep 2001). "Microtubule-associated protein-2: a new sensitive and specific marker for pulmonary carcinoid tumor and small cell carcinoma.". Mod Pathol 14 (9): 880-5. doi:10.1038/modpathol.3880406. PMID 11557784.
  10. Liu, Y.; Mangini, J.; Saad, R.; Silverman, AR.; Abell, E.; Tung, MY.; Graner, SR.; Silverman, JF. (Dec 2003). "Diagnostic value of microtubule-associated protein-2 in Merkel cell carcinoma.". Appl Immunohistochem Mol Morphol 11 (4): 326-9. PMID 14663358.